Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24677207 | 0.78 | POLB (0.37) | POLBKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL12124199 | 0.74 | POLB (0.38) | POLBKMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL12160719 | 0.72 | POLB (0.37) | POLBKMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL12124456 | 0.72 | POLB (0.37) | POLBKMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL25725789 | 0.72 | POLB (0.34) | POLBKMT2ALMNA | |
| SCHEMBL15942159 | 0.71 | POLB (0.51) | POLBKMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL5393593 | 0.71 | POLB (0.36) | POLBKMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL12673219 | 0.71 | POLB (0.36) | POLBKMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL3331795 | 0.71 | CYP2C19 (0.41) | POLBKMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL21737449 | 0.69 | POLB (0.35) | POLBKMT2AMEN1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167062-A1 | AMIDE COMPOUND CONTAINING SUBSTITUTED ACETOPHENONE STRUCTURAL FRAGMENTS AND PREPARATION METHOD AND APPLICATION THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2023-06-01 | — | — | US | disclosed |
| WO-2021082997-A1 | AMIDE COMPOUND CONTAINING SUBSTITUTED ACETOPHENONE STRUCTURE FRAGMENT, PREPARATION METHOD THEREFOR AND USE THEREOF | 沈阳中化农药化工研发有限公司 | 2021-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167062-A1 | AMIDE COMPOUND CONTAINING SUBSTITUTED ACETOPHENONE STRUCTURAL FRAGMENTS AND PREPARATION METHOD AND APPLICATION THEREOF | AADAC, AAK1, ACLY | POLB 4341/4885KMT2A 2028/4885MEN1 2560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.