Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19001131 | 1.00 | HRH3 (0.52) | HRH3MEN1KMT2AL3MBTL3L3MBTL1 | |
| SCHEMBL19001066 | 1.00 | HRH3 (0.52) | HRH3MEN1KMT2AL3MBTL3L3MBTL1 | |
| SCHEMBL23328251 | 0.86 | KDM2B (0.53) | HRH3MEN1KMT2AL3MBTL3L3MBTL1 | |
| SCHEMBL12125866 | 0.84 | L3MBTL3 (0.51) | HRH3MEN1KMT2AL3MBTL3L3MBTL1 | |
| SCHEMBL10202402 | 0.84 | L3MBTL3 (0.51) | HRH3MEN1KMT2AL3MBTL3L3MBTL1 | |
| SCHEMBL12125869 | 0.84 | L3MBTL3 (0.51) | HRH3MEN1KMT2AL3MBTL3L3MBTL1 | |
| SCHEMBL24123749 | 0.84 | L3MBTL1 (0.50) | HRH3MEN1KMT2AL3MBTL3L3MBTL1 | |
| SCHEMBL25675635 | 0.84 | L3MBTL1 (0.46) | HRH3MEN1KMT2AL3MBTL3L3MBTL1 | |
| SCHEMBL23328577 | 0.83 | ALDH1A1 (0.51) | MEN1KMT2A | |
| SCHEMBL22187761 | 0.83 | ALDH1A1 (0.51) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365196-B2 | FGFR inhibitor and application thereof | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2022-06-21 | — | — | US | disclosed |
| US-20210130353-A1 | FGFR INHIBITOR AND APPLICATION THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365196-B2 | FGFR inhibitor and application thereof | FGFR1, FGFR4, FGFR2 | HRH3 4083/4885MEN1 4125/4885KMT2A 3253/4885 |
| US-20210130353-A1 | FGFR INHIBITOR AND APPLICATION THEREOF | FGFR1, FGFR4, FGFR2 | HRH3 4216/4885MEN1 4490/4885KMT2A 3272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.