SCHEMBL23328303

SCHEMBL23328303

C=CC(=O)N1CCN(CCCC(C)(C)C)C(C)(C)C1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.37
JAK3 P52333 2/20 0.32
CHRM1 P11229 1/20 0.30
SLC29A1 Q99808 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23328270 0.76 TEAD3 (0.47) FGFR1
SCHEMBL23328306 0.76 TEAD3 (0.35)
SCHEMBL21741286 0.72 JAK3 (0.36) JAK3
SCHEMBL22967502 0.71 JAK3 (0.34) JAK3
SCHEMBL23328749 0.69 FGFR1 (0.35) FGFR1
SCHEMBL23328750 0.69 FGFR1 (0.38) FGFR1JAK3
SCHEMBL23328272 0.68 TEAD1 (0.49) FGFR1JAK3
SCHEMBL23328297 0.68 THRA (0.33) FGFR1JAK3
SCHEMBL22969801 0.67 JAK3 (0.35) JAK3
SCHEMBL20314920 0.65 JAK3 (0.38) JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11365196-B2 FGFR inhibitor and application thereof BETTA PHARMACEUTICALS CO., LTD. (CN) 2022-06-21 US disclosed
US-20210130353-A1 FGFR INHIBITOR AND APPLICATION THEREOF BETTA PHARMACEUTICALS CO., LTD. (CN) 2021-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11365196-B2 FGFR inhibitor and application thereof FGFR1, FGFR4, FGFR2 FGFR1 1/4885JAK3 196/4885CHRM1 4838/4885
US-20210130353-A1 FGFR INHIBITOR AND APPLICATION THEREOF FGFR1, FGFR4, FGFR2 FGFR1 1/4885JAK3 153/4885CHRM1 4844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.