Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD3 | Q99594 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | TET3 | O43151 | 4/20 | 0.35 |
| ▸ | FBXL19 | Q6PCT2 | 4/20 | 0.35 |
| ▸ | CXXC5 | Q7LFL8 | 4/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.35 |
| ▸ | CXXC4 | Q9H2H0 | 4/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.35 |
| ▸ | TET1 | Q8NFU7 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GPR183 | P32249 | 1/20 | 0.30 |
| ▸ | SPR | P35270 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23328270 | 0.83 | TEAD3 (0.47) | TEAD3KMT2AMEN1GPR183 | |
| SCHEMBL22849040 | 0.78 | GPR183 (0.40) | TEAD3KMT2ATET3FBXL19CXXC5 | |
| SCHEMBL23328303 | 0.76 | FGFR1 (0.37) | — | |
| SCHEMBL26455634 | 0.75 | CYP1A2 (0.40) | CYP2D6TSHR | |
| SCHEMBL23328300 | 0.75 | CYP2D6 (0.39) | TEAD3KMT2ATET3FBXL19CXXC5 | |
| SCHEMBL25904074 | 0.73 | CYP2D6 (0.38) | KMT2ACYP2D6MEN1USP2CYP3A4 | |
| SCHEMBL23695982 | 0.73 | CYP2D6 (0.37) | KMT2ACYP2D6MEN1USP2CYP3A4 | |
| SCHEMBL23328703 | 0.73 | KMT2A (0.40) | KMT2ATET3FBXL19CXXC5KDM2B | |
| SCHEMBL23328749 | 0.72 | FGFR1 (0.35) | TEAD3KMT2AMEN1 | |
| SCHEMBL23328553 | 0.71 | KMT2A (0.41) | KMT2ATET3FBXL19CXXC5KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365196-B2 | FGFR inhibitor and application thereof | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2022-06-21 | — | — | US | disclosed |
| US-20210130353-A1 | FGFR INHIBITOR AND APPLICATION THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365196-B2 | FGFR inhibitor and application thereof | FGFR1, FGFR4, FGFR2 | TEAD3 1649/4885KMT2A 3253/4885TET3 4452/4885 |
| US-20210130353-A1 | FGFR INHIBITOR AND APPLICATION THEREOF | FGFR1, FGFR4, FGFR2 | TEAD3 1580/4885KMT2A 3272/4885TET3 4625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.