Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27334232 | 0.84 | GGPS1 (0.52) | PLA2G1BPLA2G2AGGPS1DNM1OPRM1 | |
| SCHEMBL21105969 | 0.82 | GGPS1 (0.50) | ACE2PLA2G1BPLA2G2AGGPS1LMNA | |
| SCHEMBL21418477 | 0.82 | GGPS1 (0.46) | ACE2PLA2G1BPLA2G2AGGPS1LMNA | |
| SCHEMBL24849421 | 0.82 | PLA2G1B (0.42) | ACE2PLA2G1BPLA2G2AGGPS1LMNA | |
| SCHEMBL23505460 | 0.82 | GGPS1 (0.48) | PLA2G1BPLA2G2AGGPS1DNM1OPRM1 | |
| SCHEMBL18383824 | 0.80 | ACE2 (0.42) | ACE2PLA2G1BPLA2G2ALMNADNM1 | |
| SCHEMBL12663272 | 0.80 | PLA2G1B (0.39) | ACE2PLA2G1BPLA2G2AGGPS1LMNA | |
| SCHEMBL19936946 | 0.80 | GGPS1 (0.41) | GGPS1DNM1 | |
| SCHEMBL19703518 | 0.80 | ACE2 (0.45) | ACE2PLA2G1BPLA2G2ALMNADNM1 | |
| SCHEMBL23568339 | 0.79 | LMNA (0.41) | PLA2G1BPLA2G2AGGPS1LMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210130359-A1 | SULFONYLUREAS AND SULFONYLTHIOUREAS AS NLRP3 INHIBITORS | INFLAZOME LIMITED (IE) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130359-A1 | SULFONYLUREAS AND SULFONYLTHIOUREAS AS NLRP3 INHIBITORS | NLRP3, NOD1, NLRP1 | ACE2 1995/4885PLA2G1B 4480/4885PLA2G2A 4515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.