SCHEMBL23328679

SCHEMBL23328679

N#Cc1ccc(-c2ccc(N(c3ccc(-c4ccc(C#N)c5ccccc45)cc3)c3ccc(-c4cccc5c4oc4ccccc45)cc3)cc2)c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.46
GGPS1 O95749 1/20 0.35
PRKDC P78527 4/20 0.35
PTGES2 Q9H7Z7 1/20 0.33
SLC22A12 Q96S37 3/20 0.33
AR P10275 1/20 0.33
ESR2 Q92731 1/20 0.33
TNKS O95271 1/20 0.32
IMPDH2 P12268 1/20 0.32
IMPDH1 P20839 1/20 0.32
CCNT1 O60563 1/20 0.32
CDK9 P50750 1/20 0.32
CDC14B O60729 2/20 0.32
CDC14A Q9UNH5 2/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CB P42338 1/20 0.32
ADORA2A P29274 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23328441 0.91 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2SLC22A12
SCHEMBL23328765 0.89 ALOX5 (0.37) ALOX5SLC22A12ARTNKSIMPDH2
SCHEMBL25543478 0.89 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2ESR2
SCHEMBL25546983 0.89 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2ESR2
SCHEMBL23328768 0.88 ALOX5 (0.47) ALOX5GGPS1PRKDCPTGES2ESR2
SCHEMBL25544526 0.88 ALOX5 (0.47) ALOX5GGPS1PRKDCPTGES2ESR2
SCHEMBL25543174 0.87 ALOX5 (0.46) ALOX5GGPS1PRKDCPTGES2ESR2
SCHEMBL25543719 0.86 ALOX5 (0.45) ALOX5GGPS1PRKDCPTGES2TNKS
SCHEMBL25543726 0.86 ALOX5 (0.45) ALOX5GGPS1PRKDCPTGES2TNKS
SCHEMBL25544697 0.86 ALOX5 (0.45) ALOX5GGPS1PRKDCPTGES2ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021085817-A2 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 랩토 2021-05-06 WO disclosed