SCHEMBL23328765

SCHEMBL23328765

N#Cc1ccc(-c2ccc(N(c3ccc(-c4ccc(C#N)c5ccccc45)cc3)c3cccc4c3oc3ccccc34)cc2)c2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.37
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
AR P10275 1/20 0.32
TNKS O95271 1/20 0.32
CCNT1 O60563 1/20 0.32
CDK9 P50750 1/20 0.32
IMPDH2 P12268 1/20 0.31
IMPDH1 P20839 1/20 0.31
ADORA2A P29274 1/20 0.31
CYP19A1 P11511 2/20 0.30
CYP17A1 P05093 1/20 0.30
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30
SLC22A12 Q96S37 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23328679 0.89 ALOX5 (0.46) ALOX5ARTNKSCCNT1CDK9
SCHEMBL23328934 0.86 ALOX5 (0.37) ALOX5KDM4EALDH1A1GAAMAPT
SCHEMBL23328441 0.85 ALOX5 (0.44) ALOX5KDM4EALDH1A1GAAMAPT
SCHEMBL25543717 0.84 ALDH1A1 (0.37) ALOX5KDM4EALDH1A1GAAMAPT
SCHEMBL25543172 0.84 ALOX5 (0.36) ALOX5KDM4EALDH1A1GAAMAPT
SCHEMBL25548648 0.84 ALOX5 (0.36) ALOX5KDM4EALDH1A1GAAMAPT
SCHEMBL21206182 0.83 ALOX5 (0.43) ALOX5KDM4EALDH1A1MAPTAR
SCHEMBL25544703 0.83 ALOX5 (0.37) ALOX5KDM4EALDH1A1GAAMAPT
SCHEMBL23328931 0.83 TNKS (0.45) ALOX5ARTNKSCCNT1CDK9
SCHEMBL14325126 0.83 TNKS (0.45) ALOX5ARTNKSCCNT1CDK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021085817-A2 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 랩토 2021-05-06 WO disclosed