SCHEMBL25544697

SCHEMBL25544697

N#Cc1ccc(-c2ccc(N(c3ccc(-c4cccc5c4oc4ccccc45)cc3)c3ccc(C#N)c(C#N)c3)cc2)cc1C#N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.45
GGPS1 O95749 1/20 0.35
PRKDC P78527 6/20 0.35
PTGES2 Q9H7Z7 1/20 0.33
TNKS O95271 1/20 0.32
CCNT1 O60563 1/20 0.32
CDK9 P50750 1/20 0.32
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 2/20 0.32
HTT P42858 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
ATM Q13315 1/20 0.31
MCL1 Q07820 1/20 0.31
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25544526 0.98 ALOX5 (0.47) ALOX5GGPS1PRKDCPTGES2TNKS
SCHEMBL23328768 0.98 ALOX5 (0.47) ALOX5GGPS1PRKDCPTGES2TNKS
SCHEMBL25546983 0.97 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2TNKS
SCHEMBL25543478 0.97 ALOX5 (0.48) ALOX5GGPS1PRKDCPTGES2TNKS
SCHEMBL25543726 0.96 ALOX5 (0.45) ALOX5GGPS1PRKDCPTGES2TNKS
SCHEMBL25543719 0.96 ALOX5 (0.45) ALOX5GGPS1PRKDCPTGES2TNKS
SCHEMBL25544696 0.95 ALOX5 (0.43) ALOX5GGPS1PRKDCPTGES2TNKS
SCHEMBL25543174 0.94 ALOX5 (0.46) ALOX5GGPS1PRKDCPTGES2TNKS
SCHEMBL25544623 0.94 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2TNKS
SCHEMBL25544248 0.94 ALOX5 (0.44) ALOX5GGPS1PRKDCPTGES2TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-09-21 US disclosed
EP-4183784-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Lapto Co., Ltd. (KR) 2023-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301181-A1 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SAT1, FTO, SETDB1 ALOX5 2036/4885GGPS1 3576/4885PRKDC 2559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.