Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447342 | 1.00 | POLB (0.57) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL1562514 | 1.00 | POLB (0.57) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL232155 | 1.00 | POLB (0.57) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL342384 | 1.00 | POLB (0.57) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL146245 | 0.98 | POLB (0.55) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL148938 | 0.94 | LMNA (0.60) | POLBAPEX1HTTTDP1TSHR | |
| Lithium SCHEMBL30708617 | 0.92 | LMNA (0.58) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL29315991 | 0.91 | POLB (0.52) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL29315990 | 0.91 | POLB (0.52) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL14321912 | 0.90 | TSHR (0.59) | POLBAPEX1HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102283-A | Super-temperature-resistant high MB-value-resistant adsorption type polycarboxylate superplasticizer and preparation method thereof | 广西云鹰新材料科技有限公司 | 2023-05-12 | — | — | CN | claimed |
| EP-2814523-B1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS CONTAINING A MULTI-ARM PEG MACROMER | NOVARTIS AG (CH) | 2016-04-06 | — | — | EP | claimed |
| CN-104136050-B | Containing the ophthalmology and otorhinolaryngology device materials of multi-arm PEG macromonomer | NOVARTIS AG (CH) | 2015-12-02 | — | — | CN | claimed |
| CN-105102437-A | UV-absorbers for ophthalmic lens materials | NOVARTIS AG | 2015-11-25 | — | — | CN | claimed |
| EP-2941419-A1 | UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS | Novartis AG (CH) | 2015-11-11 | — | — | EP | claimed |
| EP-2844693-B1 | 2-AMINO BENZOPHENONE UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS | NOVARTIS AG (CH) | 2015-09-30 | — | — | EP | claimed |
| WO-2015072991-A1 | UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS | NOVARTIS AG (CH) | 2015-05-21 | — | — | WO | claimed |
| US-9012581-B2 | Ophthalmic and otorhinolaryngological device materials | NOVARTIS AG (CH) | 2015-04-21 | — | — | US | claimed |
| EP-2844693-A1 | 2-AMINO BENZOPHENONE UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS | Novartis AG (CH) | 2015-03-11 | — | — | EP | claimed |
| CN-104395387-A | 2-Aminobenzophenone UV Absorbers for Ophthalmic Lens Materials | NOVARTIS AG | 2015-03-04 | — | — | CN | claimed |
| US-20060036022-A1 | Covalently-bound, hydrophilic coating compositions for surgical implants | ALCON INC. (CH) | 2006-02-16 | — | — | US | claimed |
| EP-1210380-B1 | FOLDABLE OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON INC (CH) | 2005-03-16 | — | — | EP | claimed |
| US-6723815-B2 | INTRAOCULAR LENSES AND CONTACT LENSES; HYDROPHOBIC ARYL ACRYLIC MONOMER, A HYDROPHILIC MONOMER SELECTED FROM HYDROXYALKYL (METH)ACRYLATES, N-VINYL PYRROLIDONE AND ACRYLAMIDES, AND A REACTIVE PLASTICIZER | ALCON, INC. (CH) | 2004-04-20 | — | — | US | claimed |
| US-6653422-B2 | Crosslinked acrylic ester copolymer; ultraviolet and blue light absorbers; contact lenses, keratoprostheses, corneal inlays or rings; otological ventilation tubes and nasal implants; intraocular lenses | ALCON UNIVERSAL LTD. (CH) | 2003-11-25 | — | — | US | claimed |
| US-20030208013-A1 | Covalently-bound, hydrophilic coating compositions for surgical implants | ALCON INC. (CH) | 2003-11-06 | — | — | US | claimed |
| US-20030130460-A1 | Foldable ophthalmic and otorhinolaryngological device materials | ALCON INC. (CH) | 2003-07-10 | — | — | US | claimed |
| US-6528602-B1 | Intraocular lens; phenylalkyl methacrylate monomers; crosslinking agent is an methacrylated polyoxyethylene glycol | ALCON UNIVERSAL LTD. (CH) | 2003-03-04 | — | — | US | claimed |
| EP-1210380-A1 | FOLDABLE OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | Alcon Universal, Ltd. (CH) | 2002-06-05 | — | — | EP | claimed |
| WO-2001018078-A1 | FOLDABLE OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON UNIVERSAL LTD. (CH) | 2001-03-15 | — | — | WO | claimed |
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | claimed |