Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL233287 | 0.98 | POLB (0.57) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL342384 | 0.98 | POLB (0.57) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL1562514 | 0.98 | POLB (0.57) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL232155 | 0.98 | POLB (0.57) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL4447342 | 0.98 | POLB (0.57) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL148938 | 0.95 | LMNA (0.60) | POLBAPEX1HTTTDP1LMNA | |
| Lithium SCHEMBL30708617 | 0.94 | LMNA (0.58) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL29315988 | 0.91 | POLB (0.50) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL29315991 | 0.90 | POLB (0.52) | POLBAPEX1HTTTDP1LMNA | |
| SCHEMBL29315990 | 0.90 | POLB (0.52) | POLBAPEX1HTTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 964 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC (CH) | 2026-01-01 | — | — | US | claimed |
| US-12379611-B2 | Diffractive contact lenses | ALCON INC. (CH) | 2025-08-05 | — | — | US | claimed |
| EP-4522665-A1 | RADIATION INDUCED RADICAL CURING BY SEMICONDUCTING NANOPARTICLES | Yeda Research and Development Co. Ltd (IL) | 2025-03-19 | — | — | EP | claimed |
| CN-115298573-B | High refractive index silicone insert materials for embedded contact lenses | 爱尔康公司 | 2024-09-06 | — | — | CN | claimed |
| EP-4121802-B1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | ALCON INC (CH) | 2024-07-17 | — | — | EP | claimed |
| US-20240142665-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2024-05-02 | — | — | US | claimed |
| EP-4356169-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-04-24 | — | — | EP | claimed |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2024-04-11 | — | — | US | claimed |
| CN-117280252-A | Multifocal diffractive silicone hydrogel contact lenses | 爱尔康公司 | 2023-12-22 | — | — | CN | claimed |
| EP-4284787-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-12-06 | — | — | EP | claimed |
| EP-1080382-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | Alcon Laboratories, Inc. (US) | 2001-03-07 | — | — | EP | claimed |
| WO-2000079312-A1 | HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-12-28 | — | — | WO | claimed |
| US-6001128-A | CROSSLINKED ACRYLATED ESTER | ALCON LABORATORIES, INC. (US) | 1999-12-14 | — | — | US | claimed |
| WO-1999053347-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON LABORATORIES, INC. (US) | 1999-10-21 | — | — | WO | claimed |
| EP-0914169-A2 | MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES | ALCON LABORATORIES, INC. (US) | 1999-05-12 | — | — | EP | claimed |
| WO-1998053862-A2 | MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES | ALCON LABORATORIES, INC. (US) | 1998-12-03 | — | — | WO | claimed |
| US-5693095-A | CROSSLINKED ACRYLIC COPOLYMERS, SUITABLE FOR SOFT, FOLDABLE EYE LENSES | ALCON LABORATORIES, INC. (US) | 1997-12-02 | — | — | US | claimed |
| EP-0774983-A1 | IMPROVED HIGH REFRACTIVE INDEX OPHTHALMIC LENS MATERIALS | ALCON LABORATORIES, INC. (US) | 1997-05-28 | — | — | EP | claimed |
| WO-1996040303-A1 | IMPROVED HIGH REFRACTIVE INDEX OPHTHALMIC LENS MATERIALS | ALCON LABORATORIES, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| US-4139391-A | AN UNSATURATED COMPOUND, A PHOTOINITIATOR AND AN ACRYLIC OR METHACRYLIC ACID COPOLYMER WITH AN ACRYLIC OR METHACRYLIC ESTER, PHOTORESISTS, ALKALI RESISTANCE | FUJI PHOTO FILM CO., LTD. (JP) | 1979-02-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | LBR, CRYZ, CRYAA | POLB 1444/4885APEX1 1735/4885HTT 3394/4885 |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, UACA, PDE6A | POLB 1077/4885APEX1 111/4885HTT 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.