Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447342 | 1.00 | POLB (0.57) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL1562514 | 1.00 | POLB (0.57) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL233287 | 1.00 | POLB (0.57) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL342384 | 1.00 | POLB (0.57) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL146245 | 0.98 | POLB (0.55) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL148938 | 0.94 | LMNA (0.60) | POLBAPEX1HTTTDP1TSHR | |
| Lithium SCHEMBL30708617 | 0.92 | LMNA (0.58) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL29315991 | 0.91 | POLB (0.52) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL29315990 | 0.91 | POLB (0.52) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL14321912 | 0.90 | TSHR (0.59) | POLBAPEX1HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12232951-B2 | Optical material and method for modifying the refractive index | UNIVERSITY OF ROCHESTER (US) | 2025-02-25 | — | — | US | disclosed |
| US-20210128294-A1 | Optical Material and Method for Modifying the Refractive Index | UNIV ROCHESTER (US) | 2021-05-06 | — | — | US | disclosed |
| US-10893936-B2 | Optical device and method for modifying the refractive index of an optical material | UNIVERSITY OF ROCHESTER (US) | 2021-01-19 | — | — | US | disclosed |
| US-10806567-B2 | Optical material and method for modifying the refractive index | UNIVERSITY OF ROCHESTER (US) | 2020-10-20 | — | — | US | disclosed |
| EP-3424965-B1 | CROSSLINK AGENTS AND ITS USE | BAUSCH & LOMB (US) | 2020-05-13 | — | — | EP | disclosed |
| US-10543076-B2 | Optical material and method for modifying the refractive index | UNIVERSITY OF ROCHESTER (US) | 2020-01-28 | — | — | US | disclosed |
| US-20190240002-A1 | OPTICAL DEVICE AND METHOD FOR MODIFYING THE REFRACTIVE INDEX OF AN OPTICAL MATERIAL | UNIV ROCHESTER (US) | 2019-08-08 | — | — | US | disclosed |
| US-10299909-B2 | Optical device and method for modifying the refractive index of an optical material | UNIVERSITY OF ROCHESTER (US) | 2019-05-28 | — | — | US | disclosed |
| EP-3424965-A1 | CROSSLINK AGENTS AND DUAL RADICAL CURE POLYMER | Bausch & Lomb Incorporated (US) | 2019-01-09 | — | — | EP | disclosed |
| EP-2167555-B1 | CROSSLINK AGENTS AND DUAL RADICAL CURE POLYMER | BAUSCH & LOMB (US) | 2018-10-10 | — | — | EP | disclosed |
| WO-2006138190-A1 | HIGH REFRACTIVE-INDEX, HYDROPHILIC, ARYLSILOXY-CONTAINING MONOMERS AND POLYMERS, AND OPHTHALMIC DEVICES COMPRISING SUCH POLYMERS | BAUSCH & LOMB INCORPORATED (US) | 2006-12-28 | — | — | WO | disclosed |
| WO-2006138193-A1 | HIGH REFRACTIVE-INDEX, HYDROPHILIC, ARYLSILOXY-CONTAINING MACROMONOMERS AND POLYMERS, AND OPHTHALMIC DEVICES COMPRISING SUCH POLYMERS | BAUSCH & LOMB INCORPORATED (US) | 2006-12-28 | — | — | WO | disclosed |
| US-20060287455-A1 | High refractive-index, hydrophilic, arylsiloxy-containing macromonomers and polymers, and ophthalmic devices comprising such polymers | BAUSCH & LOMB INCORPORATED | 2006-12-21 | — | — | US | disclosed |
| US-20060286147-A1 | High refractive-index, hydrophilic, arylsiloxy-containing monomers and polymers, and ophthalmic devices comprising such polymers | BAUSCH & LOMB INCORPORATED | 2006-12-21 | — | — | US | disclosed |
| WO-2006130402-A2 | HIGH REFRACTIVE-INDEX, HYDROPHILIC MONOMERS AND POLYMERS, AND OPHTHALMIC DEVICES COMPRISING SUCH POLYMERS | BAUSCH & LOMB INCORPORATED (US) | 2006-12-07 | — | — | WO | disclosed |
| US-20060270749-A1 | High refractive-index, hydrophilic monomers and polymers, and ophthalmic devices comprising such polymers | BAUSCH & LOMB INCORPORATED | 2006-11-30 | — | — | US | disclosed |
| EP-1519968-A1 | LOW WATER CONTENT HIGH REFRACTIVE INDEX, FLEXIBLE, POLYMERIC COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2005-04-06 | — | — | EP | disclosed |
| US-6852793-B2 | Low water content, high refractive index, flexible, polymeric compositions | BAUSCH & LOMB INCORPORATED (US) | 2005-02-08 | — | — | US | disclosed |
| WO-2004000901-A1 | LOW WATER CONTENT HIGH REFRACTIVE INDEX, FLEXIBLE, POLYMERIC COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2003-12-31 | — | — | WO | disclosed |
| US-20030236375-A1 | Low water content, high refractive index, flexible, polymeric compositions | MEDICIS PHARMACEUTICAL CORPORATION | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060286147-A1 | High refractive-index, hydrophilic, arylsiloxy-containing monomers and polymers, and ophthalmic devices comprising such polymers | FANCI, UACA, PITHD1 | POLB 4034/4885APEX1 1312/4885HTT 2859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.