Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.42 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 8/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 8/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11509763 | 0.85 | RXFP1 (0.42) | MAPK1ALDH1A1KMT2A | |
| SCHEMBL14234069 | 0.84 | KDM4E (0.45) | ALDH1A1 | |
| SCHEMBL28030315 | 0.82 | XDH (0.51) | KMT2A | |
| SCHEMBL28305325 | 0.81 | XDH (0.54) | KMT2AMKNK1MKNK2 | |
| SCHEMBL11016327 | 0.80 | CCNT1 (0.45) | MAPK1PARP1 | |
| SCHEMBL13078874 | 0.80 | METAP2 (0.32) | — | |
| SCHEMBL22530619 | 0.79 | ALDH1A1 (0.50) | MAPK1ALDH1A1KMT2ACA1CA2 | |
| SCHEMBL27804563 | 0.77 | MAPT (0.43) | MAPK1ALDH1A1KMT2AMKNK1MKNK2 | |
| SCHEMBL23304045 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KMT2A | |
| SCHEMBL11697638 | 0.76 | PTPN1 (0.41) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097600-A1 | SCREENING METHOD AND COMPOUNDS FOR MODULATING TELOMERASE ACTIVITY | THE WISTAR INSTITUTE (US) | 2011-08-11 | — | — | WO | disclosed |