Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 10/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PANK3 | Q9H999 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3440289 | 0.84 | MAPT (0.55) | ALDH1A1MAPTMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL785834 | 0.82 | KMT2A (0.50) | MAPTMAPK1KDM4EGAA | |
| SCHEMBL20004338 | 0.80 | HRH3 (0.50) | HRH3ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8728954 | 0.80 | ADRB1 (0.50) | ALDH1A1MAPTSMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL15187981 | 0.80 | HRH3 (0.50) | HRH3ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL10147276 | 0.80 | USP2 (0.54) | HRH3ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL20883550 | 0.80 | RORC (0.51) | ALDH1A1MAPTMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL20251137 | 0.79 | MAPT (0.51) | HRH3ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL21590255 | 0.79 | NPY5R (0.46) | HRH3L3MBTL1HRH4 | |
| SCHEMBL22837853 | 0.79 | LTA4H (0.41) | ALDH1A1MAPTSMN1; SMN2L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365196-B2 | FGFR inhibitor and application thereof | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2022-06-21 | — | — | US | disclosed |
| US-20210130353-A1 | FGFR INHIBITOR AND APPLICATION THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365196-B2 | FGFR inhibitor and application thereof | FGFR1, FGFR4, FGFR2 | HRH3 4083/4885ALDH1A1 748/4885MAPT 3243/4885 |
| US-20210130353-A1 | FGFR INHIBITOR AND APPLICATION THEREOF | FGFR1, FGFR4, FGFR2 | HRH3 4216/4885ALDH1A1 642/4885MAPT 3081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.