SCHEMBL2333288

SCHEMBL2333288

CC(c1ccc(C(=O)Oc2ccccc2)cc1)[Bi](C)C

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
PARP10 Q53GL7 1/20 0.49
PRSS1 P07477 2/20 0.48
ACR P10323 2/20 0.48
TMPRSS15 P98073 2/20 0.48
KMT2A Q03164 4/20 0.46
ALDH1A1 P00352 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PKM P14618 1/20 0.46
NSD2 O96028 1/20 0.45
MEN1 O00255 3/20 0.44
ELANE P08246 1/20 0.43
PDCD1 Q15116 1/20 0.41
CD274 Q9NZQ7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8422497 0.83 PRSS1 (0.61) MAPTSMN1; SMN2PARP10PRSS1ACR
SCHEMBL27662315 0.81 PARP10 (0.51) MAPTSMN1; SMN2PARP10PRSS1ACR
SCHEMBL677913 0.81 PARP10 (0.51) MAPTSMN1; SMN2PARP10PRSS1ACR
SCHEMBL678241 0.81 PARP10 (0.51) MAPTSMN1; SMN2PARP10PRSS1ACR
SCHEMBL28051390 0.79 MAPT (0.50) MAPTSMN1; SMN2PARP10PRSS1ACR
SCHEMBL70034 0.79 PARP10 (0.70) MAPTSMN1; SMN2PARP10PRSS1ACR
SCHEMBL2326562 0.78 CA1 (0.52) MAPTKMT2AALDH1A1TDP1L3MBTL1
SCHEMBL2329310 0.78 ALDH1A1 (0.52) MAPTSMN1; SMN2KMT2AALDH1A1TDP1
SCHEMBL677856 0.78 MAPT (0.49) MAPTSMN1; SMN2PARP10PRSS1ACR
SCHEMBL1789851 0.78 ALDH1A1 (0.53) MAPTSMN1; SMN2PARP10PRSS1ACR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2133357-B1 LIVING RADICAL POLYMERIZATION PROMOTER OTSUKA CHEMICAL CO LTD (JP) 2016-11-16 EP disclosed
US-8076430-B2 Living radical polymerization promoter OTSUKA CHEMICAL CO., LTD. (JP) 2011-12-13 US disclosed
EP-1829883-B1 ORGANIC BISMUTH COMPOUND, METHOD FOR PRODUCING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, METHOD FOR PRODUCING POLYMER USING SAME, AND POLYMER OTSUKA CHEMICAL CO LTD (JP) 2011-08-17 EP disclosed
US-7847043-B2 Organic bismuth compound, method for producing same, living radical polymerization initiator, method for producing polymer using same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2010-12-07 US disclosed
US-20100022728-A1 LIVING RADICAL POLYMERIZATION PROMOTER OTSUKA CHEMICAL CO., LTD. (JP) 2010-01-28 US disclosed
EP-2133357-A1 LIVING RADICAL POLYMERIZATION PROMOTER Otsuka Chemical Holdings Co., Ltd. (JP) 2009-12-16 EP disclosed
US-20070265404-A1 Organic Bismuth Compound, Method for Producing Same, Living Radical Polymerization Initiator, Method for Producing Polymer Using Same, and Polymer OTSUKA CHEMICAL CO., LTD. (JP) 2007-11-15 US disclosed
EP-1829883-A1 ORGANIC BISMUTH COMPOUND, METHOD FOR PRODUCING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, METHOD FOR PRODUCING POLYMER USING SAME, AND POLYMER Otsuka Chemical Co., Ltd. (JP) 2007-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070265404-A1 Organic Bismuth Compound, Method for Producing Same, Living Radical Polymerization Initiator, Method for Producing Polymer Using Same, and Polymer DOHH, COASY, ODC1 MAPT 3794/4885SMN1; SMN2 3616/4885PARP10 3804/4885
US-20100022728-A1 LIVING RADICAL POLYMERIZATION PROMOTER DNMT1, CYP1B1, DNMT3B MAPT 4496/4885SMN1; SMN2 3251/4885PARP10 1931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.