Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22304541 | 0.88 | TRPV6 (0.37) | ALDH1A1KDM4ETRPV6KMT2A | |
| SCHEMBL18177837 | 0.84 | SIGMAR1 (0.41) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL15696998 | 0.84 | SIGMAR1 (0.38) | ALDH1A1KDM4ETRPV6KMT2A | |
| SCHEMBL24802214 | 0.83 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1L3MBTL3ACHEDRD2 | |
| SCHEMBL13713265 | 0.83 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1L3MBTL3NCF1KDM4E | |
| SCHEMBL24453215 | 0.83 | SIGMAR1 (0.31) | TRPV6KMT2A | |
| SCHEMBL18026602 | 0.82 | SIGMAR1 (0.44) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL14354978 | 0.82 | SIGMAR1 (0.44) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL12772414 | 0.80 | HRH3 (0.42) | ALDH1A1L3MBTL1L3MBTL3KDM4EHRH3 | |
| SCHEMBL18032442 | 0.80 | HRH3 (0.39) | ALDH1A1L3MBTL1L3MBTL3HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053238-B2 | Benzimidazole derivatives, preparation methods and uses thereof | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2021-07-06 | — | — | US | disclosed |
| US-20210130345-A1 | BENZIMIDAZOLE DERIVATIVES, PREPARATION METHODS AND USES THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130345-A1 | BENZIMIDAZOLE DERIVATIVES, PREPARATION METHODS AND USES THEREOF | CDK6, CDK4, CDK3 | ALDH1A1 1568/4885L3MBTL1 1107/4885L3MBTL3 1181/4885 |
| US-11053238-B2 | Benzimidazole derivatives, preparation methods and uses thereof | CDK6, CDK4, CDK3 | ALDH1A1 1568/4885L3MBTL1 1107/4885L3MBTL3 1181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.