Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MITF | O75030 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5958782 | 0.82 | CYP19A1 (0.65) | HSD17B10MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27815805 | 0.81 | GPR35 (0.52) | HSD17B10MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5958789 | 0.81 | HSP90AA1 (0.59) | HSD17B10MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL28366256 | 0.79 | ACHE (0.57) | ACHEHSD17B10MAPTMEN1KMT2A | |
| SCHEMBL2137448 | 0.79 | CYP19A1 (0.67) | ACHEHSD17B10MAPTMEN1KMT2A | |
| SCHEMBL28300093 | 0.78 | GPR35 (0.58) | HSD17B10MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL16656172 | 0.78 | HSP90AA1 (0.47) | ACHEHSD17B10MAPTMEN1KMT2A | |
| SCHEMBL2822069 | 0.77 | ALDH1A1 (0.58) | HSD17B10MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL628918 | 0.76 | ACHE (0.86) | ACHEHSD17B10MAPTMEN1KMT2A | |
| Trinitrotoluene SCHEMBL20676 | 0.73 | ALDH1A1 (0.61) | HSD17B10MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1126788-B1 | SYSTEM FOR RADIOGRAPHIC IMAGING OF TISSUE | VERITAS PHARMACEUTICALS (US) | 2011-08-24 | — | — | EP | disclosed |
| US-6923950-B2 | System and method for radiographic imaging of tissue | VERITAS PHARMACEUTICALS, INC. (US) | 2005-08-02 | — | — | US | disclosed |
| US-20030091508-A1 | System and method for radiographic imaging of tissue | VERITAS PHARMACEUTICALS, INC. | 2003-05-15 | — | — | US | disclosed |
| EP-1126788-A2 | SYSTEM AND METHOD FOR RADIOGRAPHIC IMAGING OF TISSUE | Veritas Pharmaceuticals (US) | 2001-08-29 | — | — | EP | disclosed |
| US-20010001011-A1 | System and method for radiographic imaging of tissue | SALB JESSE (US) | 2001-05-10 | — | — | US | disclosed |
| US-6226352-B1 | System and method for radiographic imaging of tissue | VERITAS PHARMACEUTICALS, INC. | 2001-05-01 | — | — | US | disclosed |
| WO-2000013590-A2 | SYSTEM AND METHOD FOR RADIOGRAPHIC IMAGING OF TISSUE | VERITAS PHARMACEUTICALS (US) | 2000-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010001011-A1 | System and method for radiographic imaging of tissue | HK1, HK2, SLC2A8 | ACHE 1525/4885HSD17B10 1606/4885MAPT 3964/4885 |
| US-20030091508-A1 | System and method for radiographic imaging of tissue | HK1, HK2, SLC2A8 | ACHE 1525/4885HSD17B10 1606/4885MAPT 3964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.