Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094492 | 0.87 | SMN1; SMN2 (0.46) | TSHRSMN1; SMN2ACHENFE2L2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28571903 | 0.86 | SMN1; SMN2 (0.44) | TSHRSMN1; SMN2ACHENFE2L2ALDH1A1 | |
| SCHEMBL14471561 | 0.85 | NFE2L2 (0.51) | SMN1; SMN2NFE2L2ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL7321860 | 0.83 | ESR1 (0.46) | TSHRSMN1; SMN2ACHEESR1HIF1A | |
| SCHEMBL5285423 | 0.83 | ACHE (0.49) | SMN1; SMN2ACHEESR1HIF1AALDH1A1 | |
| SCHEMBL28538825 | 0.82 | PTPN1 (0.51) | SMN1; SMN2ACHEESR1HIF1ANFE2L2 | |
| SCHEMBL2332114 | 0.82 | ACHE (0.44) | TSHRSMN1; SMN2ACHEESR1HIF1A | |
| SCHEMBL15547744 | 0.81 | NFE2L2 (0.47) | SMN1; SMN2ACHENFE2L2ALDH1A1ALOX15 | |
| SCHEMBL362721 | 0.81 | ALDH1A1 (0.52) | TSHRSMN1; SMN2ACHEESR1HIF1A | |
| SCHEMBL27534597 | 0.80 | ESR1 (0.44) | TSHRSMN1; SMN2ACHEESR1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095218-A1 | TEMPLATE-FIXED PEP TIDOMIME TICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |