Trifluoromethanesulfonamide

Trifluoromethanesulfonamide

SCHEMBL2333486

NS(=O)(=O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 0.65
CA2 P00918 7/20 0.65
CA7 P43166 2/20 0.65
CA13 Q8N1Q1 1/20 0.65
L3MBTL1 Q9Y468 2/20 0.43
ALDH1A1 P00352 1/20 0.43
CA9 Q16790 5/20 0.36
CA5A P35218 2/20 0.36
CA12 O43570 3/20 0.35
F2 P00734 1/20 0.35
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35
TSHR P16473 1/20 0.32
NT5E P21589 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL30605511 0.88 ALDH1A1 (0.48) CA1CA2CA7CA13L3MBTL1
Trifluoroacetic Acid SCHEMBL3845260 0.82 CA1 (0.47) CA1CA2CA7CA13L3MBTL1
Trifluoroacetic Acid SCHEMBL30657138 0.82 CA1 (0.47) CA1CA2CA7CA13L3MBTL1
Trifluoromethanesulfonamide SCHEMBL29042995 0.80 CA2 (1.00) CA1CA2CA7CA13CA9
Trifluoromethanesulfonamide SCHEMBL130 0.80
Trifluoromethanesulfonamide SCHEMBL6602452 0.80
Trifluoromethanesulfonic Acid SCHEMBL991785 0.79 ALDH1A1 (0.60) CA1CA2CA7CA13L3MBTL1
Trifluoroacetic Acid SCHEMBL34466006 0.78 ALDH1A1 (0.40) CA1CA2CA7CA13L3MBTL1
Trifluoroacetic Acid SCHEMBL332728 0.78 ALDH1A1 (0.58) CA1CA2CA7CA13L3MBTL1
Trifluoromethanesulfonamide SCHEMBL23573920 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011099932-A1 SMART POLYMERS FUNCTIONALIZED HOLLOW SILICA VESICLES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-08-18 WO disclosed
US-20100254890-A1 METHOD OF FORMING A PARTICULATE POROUS METAL OXIDE OR METALLOID OXIDE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2010-10-07 US disclosed
EP-1198233-B1 SULFONAMIDE AND SULFAMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2006-08-16 EP disclosed
EP-1198233-A4 SULFONAMIDE AND SULFAMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2002-07-24 EP disclosed
EP-1198233-A1 SULFONAMIDE AND SULFAMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M Innovative Properties Company (US) 2002-04-24 EP disclosed
WO-2000076519-A1 SULFONAMIDE AND SULFAMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-12-21 WO disclosed