SCHEMBL2333604

SCHEMBL2333604

O=Cc1ccc(O)c(O)c1F

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 7/20 0.50
TRIM24 O15164 2/20 0.43
TRIM33 Q9UPN9 2/20 0.43
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
HSP90AA1 P07900 1/20 0.39
IDO1 P14902 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TYR P14679 2/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
ADRA1A P35348 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29951860 1.00 ERN1 (0.50) ERN1TRIM24TRIM33KDM4EMEN1
SCHEMBL219001 0.84 TRIM24 (0.44) ERN1TRIM24TRIM33KDM4EMEN1
SCHEMBL2263615 0.82 ERN1 (0.63) ERN1
SCHEMBL31114189 0.82 ERN1 (0.52) ERN1TRIM24TRIM33KDM4EMEN1
SCHEMBL12814036 0.82 ERN1 (0.52) ERN1TRIM24TRIM33KDM4EMEN1
SCHEMBL15195884 0.80 ERN1 (0.50) ERN1TRIM24TRIM33KDM4EMEN1
SCHEMBL14920117 0.78 ERN1 (0.44) ERN1TRIM24TRIM33MEN1NPC1
SCHEMBL14882565 0.78 ERN1 (0.44) ERN1TRIM24TRIM33TYR
SCHEMBL12593983 0.78 ERN1 (0.40) ERN1TRIM24TRIM33KDM4EMEN1
SCHEMBL29954266 0.78 ERN1 (0.48) ERN1TRIM24TRIM33KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200205541-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND L'OREAL (FR) 2020-07-02 US claimed
US-20130298933-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND L'OREAL (FR) 2013-11-14 US claimed
EP-2358338-B1 DYE, COMPRISING SPECIAL HALOGEN SUBSTITUTED PYROCATECHOL ALDEHYDES AND SPECIAL CH-ACIDIC COMPOUNDS HENKEL AG & CO KGAA (DE) 2013-10-16 EP claimed
EP-2358338-A2 DYE, COMPRISING SPECIAL HALOGEN-SUBSTITUTED CATECHOL-ALDEHYE AND SPECIAL CH-ACID COMPOUNDS Henkel AG & Co. KGaA (DE) 2011-08-24 EP claimed
US-20100300472-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND L'OREAL S.A. (FR) 2010-12-02 US claimed
WO-2010072511-A2 DYE, COMPRISING SPECIAL HALOGEN-SUBSTITUTED CATECHOL-ALDEHYE AND SPECIAL CH-ACID COMPOUNDS HENKEL AG & CO. KGAA (DE) 2010-07-01 WO claimed
US-11399611-B2 Process for straightening keratin fibres with a heating means and denaturing agents L'OREAL (FR) 2022-08-02 US disclosed
US-11044978-B2 Method for straightening keratinous fibers using heating means and an aromatic compound L'OREAL (FR) 2021-06-29 US disclosed
US-20200205541-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND L'OREAL (FR) 2020-07-02 US disclosed
US-20190125051-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS L'OREAL (FR) 2019-05-02 US disclosed
US-20140326268-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS L'OREAL (FR) 2014-11-06 US disclosed
US-8765107-B2 Process for straightening keratin fibres with a heating means and denaturing agents L'OREAL (FR) 2014-07-01 US disclosed
US-20130298933-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND L'OREAL (FR) 2013-11-14 US disclosed
EP-2358338-B1 DYE, COMPRISING SPECIAL HALOGEN SUBSTITUTED PYROCATECHOL ALDEHYDES AND SPECIAL CH-ACIDIC COMPOUNDS HENKEL AG & CO KGAA (DE) 2013-10-16 EP disclosed
US-20120192888-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS L 'Oréal S.A., (FR) 2012-08-02 US disclosed
EP-2358338-A2 DYE, COMPRISING SPECIAL HALOGEN-SUBSTITUTED CATECHOL-ALDEHYE AND SPECIAL CH-ACID COMPOUNDS Henkel AG & Co. KGaA (DE) 2011-08-24 EP disclosed
US-20100300472-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND L'OREAL S.A. (FR) 2010-12-02 US disclosed
WO-2010072511-A2 DYE, COMPRISING SPECIAL HALOGEN-SUBSTITUTED CATECHOL-ALDEHYE AND SPECIAL CH-ACID COMPOUNDS HENKEL AG & CO. KGAA (DE) 2010-07-01 WO disclosed
US-20100028280-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS L'OREAL S.A. (FR) 2010-02-04 US disclosed
US-3976695-A Halogen substituted α-(aminoalkyl)-3,4-dihydroxybenzyl alcohols SMITHKLINE CORPORATION (US) 1976-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120192888-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS KRT18, KRTCAP2, TUBB4A ERN1 602/4885TRIM24 891/4885TRIM33 783/4885
US-20200205541-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND KRT18, TUBB4A, TUBB4B ERN1 3359/4885TRIM24 562/4885TRIM33 441/4885
US-11399611-B2 Process for straightening keratin fibres with a heating means and denaturing agents KRT18, KRTCAP2, TUBB4A ERN1 602/4885TRIM24 891/4885TRIM33 783/4885
US-20100028280-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS KRT18, KRTCAP2, TUBB4A ERN1 602/4885TRIM24 891/4885TRIM33 783/4885
US-20190125051-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS KRT18, KRTCAP2, TUBB4A ERN1 602/4885TRIM24 891/4885TRIM33 783/4885
US-11044978-B2 Method for straightening keratinous fibers using heating means and an aromatic compound KRT18, TUBB4A, TUBB4B ERN1 3359/4885TRIM24 562/4885TRIM33 441/4885
US-20100300472-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND KRT18, TUBB4A, TUBB4B ERN1 3359/4885TRIM24 562/4885TRIM33 441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.