Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.52 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31114189 | 1.00 | ERN1 (0.52) | ERN1TRIM24TRIM33KDM4EMEN1 | |
| SCHEMBL219001 | 0.84 | TRIM24 (0.44) | ERN1TRIM24TRIM33KDM4EMEN1 | |
| SCHEMBL29715811 | 0.82 | ERN1 (0.63) | ERN1 | |
| SCHEMBL1042430 | 0.82 | ERN1 (0.63) | ERN1 | |
| SCHEMBL29951860 | 0.82 | ERN1 (0.50) | ERN1TRIM24TRIM33KDM4EMEN1 | |
| SCHEMBL2333604 | 0.82 | ERN1 (0.50) | ERN1TRIM24TRIM33KDM4EMEN1 | |
| SCHEMBL12375477 | 0.78 | ERN1 (0.48) | ERN1TRIM24TRIM33TYRTLR2 | |
| SCHEMBL16616199 | 0.78 | ERN1 (0.48) | ERN1TRIM24TRIM33TLR2TLR1 | |
| SCHEMBL20607742 | 0.78 | ERN1 (0.48) | ERN1TRIM24TRIM33KDM4EMEN1 | |
| SCHEMBL29955049 | 0.78 | ERN1 (0.48) | ERN1TRIM24TRIM33KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160340709-A1 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-11-24 | — | — | US | claimed |
| EP-2691383-A1 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF | 3M Innovative Properties Company (US) | 2014-02-05 | — | — | EP | claimed |
| CN-103476761-A | Fluorogenic or fluorophoric compounds and uses thereof | 3M INNOVATIVE PROPERTIES CO | 2013-12-25 | — | — | CN | claimed |
| WO-2012134724-A1 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-10-04 | — | — | WO | claimed |
| EP-4698520-A1 | RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF | Gandeeva Therapeutics, Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024220708-A1 | RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF | GANDEEVA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| US-11084826-B2 | RSV antiviral pyrazolo- and triazolo-pyrimidine compounds | Janssen Sciences Ireland Unlimited Company (IE) | 2021-08-10 | — | — | US | disclosed |
| US-20200223855-A1 | RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2020-07-16 | — | — | US | disclosed |
| US-9896711-B2 | Fluorogenic or fluorophoric compounds and uses thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-02-20 | — | — | US | disclosed |
| US-9896711-B2 | Fluorogenic or fluorophoric compounds and uses thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-02-20 | — | — | US | disclosed |
| US-9896711-B2 | Fluorogenic or fluorophoric compounds and uses thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-02-20 | — | — | US | disclosed |
| EP-2970339-B1 | 1-HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | LILLY CO ELI (US) | 2017-08-16 | — | — | EP | disclosed |
| WO-2014149793-A1 | 1 -HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS | ELI LILLY AND COMPANY (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20140186878-A1 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-07-03 | — | — | US | disclosed |
| US-20140186878-A1 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-07-03 | — | — | US | disclosed |
| US-20140186878-A1 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-07-03 | — | — | US | disclosed |
| EP-2691383-A1 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF | 3M Innovative Properties Company (US) | 2014-02-05 | — | — | EP | disclosed |
| CN-103476761-A | Fluorogenic or fluorophoric compounds and uses thereof | 3M INNOVATIVE PROPERTIES CO | 2013-12-25 | — | — | CN | disclosed |
| WO-2012134724-A1 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012134724-A1 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200223855-A1 | RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS | ZC3HAV1, MAVS, TYMP | ERN1 1431/4885TRIM24 1419/4885TRIM33 673/4885 |
| US-11084826-B2 | RSV antiviral pyrazolo- and triazolo-pyrimidine compounds | ZC3HAV1, MAVS, TYMP | ERN1 1431/4885TRIM24 1419/4885TRIM33 673/4885 |
| US-20140186878-A1 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF | FDPS, FOS, PFKFB1 | ERN1 2172/4885TRIM24 4386/4885TRIM33 4408/4885 |
| US-20160340709-A1 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF | FDPS, FOS, PFKFB1 | ERN1 2172/4885TRIM24 4386/4885TRIM33 4408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.