Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9983507 | 0.75 | AKR1B1 (0.41) | EPHX2CCR1HTR2AAKR1B1IRAK4 | |
| SCHEMBL15750188 | 0.73 | HRH3 (0.49) | EPHX2 | |
| SCHEMBL20274209 | 0.71 | RIPK1 (0.38) | EPHX2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9983557 | 0.71 | AKR1B1 (0.41) | EPHX2CCR1HTR2AALDH1A1KDM4E | |
| SCHEMBL20274120 | 0.68 | TSHR (0.48) | EPHX2KMT2ASMN1; SMN2RIPK1HPGD | |
| SCHEMBL9983223 | 0.68 | AKR1B1 (0.36) | CCR1HTR2AAKR1B1IRAK4 | |
| SCHEMBL15724661 | 0.67 | AKR1B1 (0.46) | HTR2AALDH1A1KDM4EAKR1B1 | |
| SCHEMBL20274167 | 0.66 | HRH3 (0.38) | EPHX2HTR2ASMN1; SMN2AKR1B1RIPK1 | |
| SCHEMBL29175438 | 0.65 | CNR1 (0.38) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL30702774 | 0.65 | CNR1 (0.38) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |