Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23336152 | 0.71 | EPHX2 (0.41) | RIPK1CYP2D6CYP2C9ALOX15TSHR | |
| SCHEMBL15750188 | 0.70 | HRH3 (0.49) | EPHX2LTA4HNTRK1ABCB1 | |
| SCHEMBL20274120 | 0.68 | TSHR (0.48) | RIPK1TSHREPHX2SMN1; SMN2KMT2A | |
| SCHEMBL20274167 | 0.66 | HRH3 (0.38) | RIPK1CYP2D6CYP2C9ALOX15TSHR | |
| SCHEMBL23336086 | 0.64 | FAAH (0.57) | CYP2D6CYP2C9ALOX15TSHRCYP2C19 | |
| SCHEMBL20274145 | 0.63 | HRH3 (0.56) | KDM1AMAOBLTA4HABCB1ABCG2 | |
| SCHEMBL20274152 | 0.63 | HTR2B (0.43) | CYP2D6CYP2C9ALOX15TSHRCYP2C19 | |
| SCHEMBL20274151 | 0.63 | FAAH (0.48) | CYP2D6CYP2C9ALOX15TSHRCYP2C19 | |
| SCHEMBL23335841 | 0.62 | L3MBTL1 (0.54) | SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1903391 | 0.62 | GRM5 (0.65) | TSHRHTTSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |