Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20651218 | 0.88 | MEN1 (0.37) | CACNA1CCHRM1RIPK1POLBDPP8 | |
| SCHEMBL15750188 | 0.79 | HRH3 (0.49) | HRH3DRD2EPHX2NTRK1 | |
| SCHEMBL20274120 | 0.78 | TSHR (0.48) | RIPK1POLBKDM1AMAOAMAOB | |
| SCHEMBL23336293 | 0.73 | ENPP2 (0.35) | HTR2AKDM1AMAOA | |
| SCHEMBL20665136 | 0.71 | HTR2A (0.47) | HRH3CACNA1CHTR2AMLNRADRB2 | |
| SCHEMBL20274145 | 0.71 | HRH3 (0.56) | HRH3HTR2ADRD2KDM1AMAOB | |
| SCHEMBL15707813 | 0.69 | HRH3 (0.51) | HRH3DRD2HTTSMN1; SMN2 | |
| SCHEMBL20274187 | 0.68 | ALDH1A1 (0.45) | HRH3CACNA1CPOLBDPP4CYP2D6 | |
| SCHEMBL20274172 | 0.68 | POLB (0.38) | HRH3CACNA1CCHRM1POLBCYP2D6 | |
| SCHEMBL20274126 | 0.67 | HRH3 (0.44) | HRH3DRD2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |