Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360730 | 0.87 | L3MBTL1 (0.47) | L3MBTL1RIPK1CYP11B1CYP11B2SRD5A2 | |
| SCHEMBL30385642 | 0.87 | RIPK1 (0.47) | PLA2G10RIPK1ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL3380852 | 0.82 | MAPT (0.46) | L3MBTL1ALDH1A1 | |
| SCHEMBL6825782 | 0.76 | PLA2G10 (0.45) | L3MBTL1PLA2G10GRM2ALDH1A1BAZ2B | |
| SCHEMBL1233408 | 0.76 | PLA2G10 (0.45) | L3MBTL1PLA2G10ALDH1A1BAZ2B | |
| SCHEMBL2360731 | 0.74 | L3MBTL1 (0.39) | L3MBTL1CYP11B1CYP11B2SRD5A2IDH1 | |
| SCHEMBL24131122 | 0.74 | RIPK1 (0.49) | RIPK1ALDH1A1CYP11B1CYP11B2IDH1 | |
| SCHEMBL23337165 | 0.73 | L3MBTL1 (0.46) | L3MBTL1NAMPTSRD5A2PARP10TRPV1 | |
| SCHEMBL1234340 | 0.73 | PLA2G10 (0.43) | L3MBTL1PLA2G10ALDH1A1BAZ2B | |
| SCHEMBL6014829 | 0.73 | NR3C2 (0.52) | GRM2SRD5A2PARP10NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3816163-A1 | CELL NECROSIS INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2021-05-05 | — | — | EP | disclosed |