Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 3/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.42 |
| ▸ | KLK1 | P06870 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17440067 | 0.84 | PLA2G2A (0.51) | NR3C2GRM2CSF1RCYP17A1 | |
| SCHEMBL29779639 | 0.82 | KLKB1 (0.63) | GRM2KLKB1KLK1 | |
| SCHEMBL6014195 | 0.80 | PARP1 (0.56) | NR3C2CSF1RKLKB1KLK1SMN1; SMN2 | |
| SCHEMBL17443023 | 0.79 | GRM2 (0.41) | NR3C2GRM2CSF1RCYP17A1 | |
| SCHEMBL2677778 | 0.78 | SMYD3 (0.54) | NPC1RAB9A | |
| SCHEMBL13728182 | 0.77 | GRM2 (0.43) | NR3C2GRM2NPC1RAB9ASRD5A2 | |
| SCHEMBL27772527 | 0.77 | MKNK1 (0.51) | NR3C2GRM2 | |
| SCHEMBL20377228 | 0.76 | CYP4F2 (0.45) | NR3C2CSF1R | |
| SCHEMBL2176535 | 0.76 | LOXL2 (0.56) | — | |
| SCHEMBL30193091 | 0.76 | RECQL (0.50) | NR3C2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298311-B1 | w-Carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors | BAYER HEALTHCARE LLC (US) | 2012-05-09 | — | — | EP | disclosed |