Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL15988300 | 0.97 | TDP1 (0.43) | TDP1ALDH1A1CYP2C19CA2ACHE | |
| SCHEMBL1924519 | 0.89 | ALDH1A1 (0.53) | TDP1ALDH1A1CYP2C19CA2ACHE | |
| SCHEMBL103502 | 0.86 | — | — | |
| SCHEMBL28357119 | 0.83 | TDP1 (0.59) | TDP1ALDH1A1CYP2C19CA2ACHE | |
| Hydrochloric Acid SCHEMBL8921344 | 0.83 | — | — | |
| SCHEMBL1948119 | 0.80 | ALDH1A1 (0.40) | TDP1ALDH1A1CYP2C19CA2ACHE | |
| SCHEMBL93369 | 0.80 | — | — | |
| SCHEMBL15209452 | 0.79 | TDP1 (0.45) | TDP1ALDH1A1CYP2C19CA2ACHE | |
| Butanone SCHEMBL29275306 | 0.79 | TDP1 (0.57) | TDP1ALDH1A1CYP2C19CA2ACHE | |
| Acetic Acid SCHEMBL8922876 | 0.79 | TDP1 (0.50) | TDP1ALDH1A1CYP2C19CA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534144-B1 | Preparation process of the sodium salt of Esomeprazole | ESTEVE QUÍMICA S A (ES) | 2014-09-03 | — | — | EP | claimed |
| US-8680284-B2 | Preparation process of the sodium salt of esomeprazole | ESTEVE QUIMICA, S.A. (ES) | 2014-03-25 | — | — | US | claimed |
| EP-2534144-A1 | PREPARATION PROCESS OF THE SODIUM SALT OF ESOMEPRAZOLE | Esteve Química, S.A. (ES) | 2012-12-19 | — | — | EP | claimed |
| US-20120309976-A1 | PREPARATION PROCESS OF THE SODIUM SALT OF ESOMEPRAZOLE | Esteve Química, S.A. (ES) | 2012-12-06 | — | — | US | claimed |
| WO-2011098553-A1 | PREPARATION PROCESS OF THE SODIUM SALT OF ESOMEPRAZOLE | Esteve Química, S.A. (ES) | 2011-08-18 | — | — | WO | claimed |
| EP-1644307-A2 | PROCESSES FOR PREPARING BETA-DIKETONE COMPOUND, METAL COMPLEX THEREOF AND METALLIC COMPOUND | Showa Denko K.K. (JP) | 2006-04-12 | — | — | EP | claimed |
| WO-2004110971-A2 | PROCESSES FOR PREPARING BETA-DIKETONE COMPOUND, METAL COMPLEX THEREOF AND METALLIC COMPOUND | SHOWA DENKO K.K. (JP) | 2004-12-23 | — | — | WO | claimed |
| CN-107207733-B | Novel crosslinking catalysts for silicone compositions | 埃肯有机硅法国简易股份公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-107001634-B | Crosslinking catalysts for silicone compositions | 埃肯有机硅法国简易股份公司 | 2020-04-24 | — | — | CN | disclosed |
| US-10023752-B2 | Conductive material and substrate | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-20170174922-A1 | CONDUCTIVE MATERIAL AND SUBSTRATE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-06-22 | — | — | US | disclosed |
| US-20170130071-A1 | CONDUCTIVE MATERIAL AND SUBSTRATE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-05-11 | — | — | US | disclosed |
| US-20170130070-A1 | CONDUCTIVE MATERIAL AND SUBSTRATE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-05-11 | — | — | US | disclosed |
| US-5665850-A | Polymeric organometallic photoinitiators and the cationically crosslinkable polyorganosiloxane compositions which comprise them | RHONE-POULENC CHIMIE (FR) | 1997-09-09 | — | — | US | disclosed |
| US-5626968-A | FOR CROSSLINKING POLYSILOXANES TO RENDER SURFACE ADHERENT, FOR ENCAPSULATION OF ELECTRONIC COMPONENTS, FOR OPTICAL FIBER SHEATHING, FOR TEXTILE COATING | RHONE-POULENC CHIMIE (FR) | 1997-05-06 | — | — | US | disclosed |
| EP-0279090-B1 | GASOLINE COMPOSITIONS CONTAINING HEXAVALENT MOLYBDENUM | AMOCO CORPORATION (US) | 1991-11-27 | — | — | EP | disclosed |
| EP-0279090-A1 | Gasoline compositions containing hexavalent molybdenum | AMOCO CORPORATION (US) | 1988-08-24 | — | — | EP | disclosed |
| US-4647293-A | Gasoline compositions containing hexavalent molybdenum | Magidson, William H. (US) | 1987-03-03 | — | — | US | disclosed |
| US-4189306-A | OCTANE RATING IMPROVERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| US-4180386-A | ANTIKNOCK FUEL ADDITIVES | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309976-A1 | PREPARATION PROCESS OF THE SODIUM SALT OF ESOMEPRAZOLE | CYP2E1, ADH1C, ADH1A | TDP1 4586/4885ALDH1A1 75/4885CYP2C19 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.