SCHEMBL23337116

SCHEMBL23337116

O=C1C(=CC=C2N(c3ccccc3)c3nc4ccccc4nc3N2c2ccccc2)C(=O)c2cc3ccccc3cc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.34
MAPT P10636 4/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
NPSR1 Q6W5P4 2/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
MCL1 Q07820 1/20 0.34
MITF O75030 1/20 0.34
LMNA P02545 1/20 0.34
PLA2G1B P04054 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
GAA P10253 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HIF1A Q16665 2/20 0.33
CES2 O00748 1/20 0.33
BCHE P06276 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849601 0.91 ILF3 (0.34) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL13325689 0.90 ALDH1A1 (0.42) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL25851000 0.86 MAPT (0.33) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL25849840 0.86 ELANE (0.43) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL23337901 0.86 NQO2 (0.33) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL23338699 0.84 ALDH1A1 (0.35) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL23337555 0.84 KDM4E (0.38) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL23337905 0.82 KMT2A (0.40) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL23337854 0.82 POLB (0.43) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL23338726 0.81 MAPT (0.33) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301121-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-09-21 US disclosed
US-20230301121-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-09-21 US disclosed
EP-3823054-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM Corporation (JP) 2021-05-19 EP disclosed
US-20210135128-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2021-05-06 US disclosed