SCHEMBL25849840

SCHEMBL25849840

Cc1ccc2c(c1)C(=O)/C(=C/C=C1N(c3ccccc3)c3nc4ccccc4nc3N1c1ccccc1)C2=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.43
TDO2 P48775 1/20 0.39
IDO2 Q6ZQW0 1/20 0.39
MAPT P10636 5/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
RAB9A P51151 4/20 0.39
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 4/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
HSD17B10 Q99714 1/20 0.38
MITF O75030 1/20 0.38
LMNA P02545 1/20 0.38
PLA2G1B P04054 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
NPC1 O15118 2/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
MAOA P21397 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13325689 0.87 ALDH1A1 (0.42) TDO2MAPTSMN1; SMN2RAB9AALDH1A1
SCHEMBL23337116 0.86 ALDH1A1 (0.34) MAPTSMN1; SMN2RAB9AALDH1A1KDM4E
SCHEMBL25849843 0.86 ELANE (0.41) ELANETDO2IDO2MAPTSMN1; SMN2
SCHEMBL25849846 0.86 ELANE (0.41) ELANETDO2IDO2MAPTSMN1; SMN2
SCHEMBL25851000 0.86 MAPT (0.33) MAPTSMN1; SMN2RAB9AALDH1A1KDM4E
SCHEMBL25849849 0.84 ELANE (0.40) ELANETDO2IDO2MAPTSMN1; SMN2
SCHEMBL25849852 0.84 ELANE (0.40) ELANETDO2IDO2MAPTSMN1; SMN2
SCHEMBL25849822 0.83 ELANE (0.39) ELANETDO2IDO2MAPTSMN1; SMN2
SCHEMBL25849863 0.82 ELANE (0.44) ELANETDO2IDO2MAPTSMN1; SMN2
SCHEMBL25849860 0.81 ELANE (0.43) ELANETDO2IDO2MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed