SCHEMBL25849601

SCHEMBL25849601

CN1/C(=C\C=C2C(=O)c3cc4ccccc4cc3C2=O)N(c2ccccc2)c2nc3ccccc3nc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ILF3 Q12906 1/20 0.34
ALDH1A1 P00352 6/20 0.33
MAPT P10636 5/20 0.33
SMN1; SMN2 Q16637 4/20 0.33
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
LMNA P02545 3/20 0.33
MITF O75030 1/20 0.33
PLA2G1B P04054 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
MCL1 Q07820 1/20 0.31
HIF1A Q16665 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
L3MBTL1 Q9Y468 4/20 0.30
TDP1 Q9NUW8 2/20 0.30
KDM4E B2RXH2 2/20 0.30
NFKB1 P19838 1/20 0.30
CASP3 P42574 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23337116 0.91 ALDH1A1 (0.34) ILF3ALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL25849612 0.89 ILF3 (0.39) ILF3ALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL25849608 0.85 ALDH1A1 (0.37) ILF3ALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL25849609 0.84 MAPK14 (0.33) ILF3ALDH1A1KDM4EHTT
SCHEMBL25849603 0.84 ILF3 (0.32) ILF3ALDH1A1MAPTSMN1; SMN2KMT2A
SCHEMBL25849611 0.84 PDE7A (0.32) ILF3
SCHEMBL25849554 0.82 DPP4 (0.36) ILF3MAPTMEN1KMT2AMCL1
SCHEMBL13325689 0.82 ALDH1A1 (0.42) ALDH1A1MAPTSMN1; SMN2MEN1KMT2A
SCHEMBL25849617 0.81 ILF3 (0.34) ILF3ALDH1A1MAPTSMN1; SMN2MEN1
SCHEMBL25849614 0.81 ILF3 (0.34) ILF3ALDH1A1MAPTSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed