SCHEMBL23337158

SCHEMBL23337158

Cc1cc(C)c(N2/C(=C\C=C3C(=O)c4cc5ccccc5cc4C3=O)N(c3c(-c4cc(Cl)cc(Cl)c4)cccc3-c3cc(Cl)cc(Cl)c3)c3nc4ccccc4nc32)c(C)c1

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30
PTPRC P08575 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23337977 0.93 KDM4E (0.31) KDM4E
SCHEMBL23338726 0.88 MAPT (0.33) KDM4ELMNAHTT
SCHEMBL23338729 0.86 DPP4 (0.34) PTPRC
SCHEMBL23337588 0.86 DPP4 (0.31)
SCHEMBL23337553 0.84 KDM4E (0.42) KDM4ELMNA
SCHEMBL23338714 0.84 LMNA (0.34) KDM4ELMNAHTT
SCHEMBL25849603 0.82 ILF3 (0.32) KDM4ELMNAHTT
SCHEMBL23338731 0.82 ANPEP (0.32)
SCHEMBL23337555 0.82 KDM4E (0.38) KDM4ELMNAHTT
SCHEMBL23337974 0.82 ALDH1A1 (0.40) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210135128-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2021-05-06 US disclosed