SCHEMBL25849603

SCHEMBL25849603

Cc1cc(C)c(N2/C(=C/C=C3C(=O)c4cc5ccccc5cc4C3=O)N(C)c3nc4ccccc4nc32)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ILF3 Q12906 1/20 0.32
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
MAPT P10636 3/20 0.31
ALDH1A1 P00352 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
NFKB1 P19838 1/20 0.30
CASP3 P42574 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
SENP8 Q96LD8 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23338726 0.93 MAPT (0.33) ILF3LMNATP53RXFP1MAPT
SCHEMBL25849608 0.92 ALDH1A1 (0.37) ILF3LMNAMAPTALDH1A1SMN1; SMN2
SCHEMBL23338714 0.89 LMNA (0.34) LMNATP53RXFP1MAPTALDH1A1
SCHEMBL25849609 0.85 MAPK14 (0.33) ILF3ALDH1A1KDM4EHTT
SCHEMBL25849611 0.85 PDE7A (0.32) ILF3
SCHEMBL25849612 0.85 ILF3 (0.39) ILF3LMNARXFP1MAPTALDH1A1
SCHEMBL25849843 0.84 ELANE (0.41) LMNATP53RXFP1MAPTALDH1A1
SCHEMBL23337974 0.84 ALDH1A1 (0.40) MAPTALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL25849601 0.84 ILF3 (0.34) ILF3LMNAMAPTALDH1A1SMN1; SMN2
SCHEMBL23337906 0.83 LMNA (0.32) LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed