Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 5/20 | 0.59 |
| ▸ | ESR1 | P03372 | 5/20 | 0.59 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.58 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.58 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23336545 | 0.89 | ESR2 (0.62) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL13299512 | 0.88 | ESR1 (0.54) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL23336948 | 0.86 | KDM4E (0.58) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL13784133 | 0.83 | TDP1 (0.51) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL16948811 | 0.82 | TP53 (0.47) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL23336939 | 0.81 | ALDH1A1 (0.63) | ALDH1A1LMNAGAAKDM4ENPC1 | |
| SCHEMBL23337192 | 0.80 | ESR2 (0.62) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL13299511 | 0.80 | ESR1 (0.54) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL9007262 | 0.79 | ESR2 (0.91) | ESR2ESR1GRIA1CACNG8CACNG2 | |
| SCHEMBL6440249 | 0.79 | ESR2 (0.91) | ESR2ESR1GRIA1CACNG8CACNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210130382-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME | LG DISPLAY CO., LTD. (KR) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130382-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME | DDT, ORC3, PPOX | ESR2 1843/4885ESR1 561/4885GRIA1 1104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.