Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 5/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | CSK | P41240 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630685 | 0.82 | POLB (0.55) | POLBACACBNR1H4GLAPARP10 | |
| SCHEMBL23332134 | 0.78 | CTSS (0.51) | PTPN1 | |
| SCHEMBL13125638 | 0.77 | POLB (0.57) | POLBACACBGLAPARP10KDM4E | |
| SCHEMBL22444787 | 0.77 | POLB (0.57) | POLBACACBGLAPARP10KDM4E | |
| SCHEMBL2803084 | 0.77 | POLB (0.60) | POLBACACBPARP10KDM4ENPC1 | |
| SCHEMBL19759402 | 0.77 | POLB (0.60) | POLBACACBPARP10KDM4ENPC1 | |
| SCHEMBL23331972 | 0.77 | PTPN1 (0.34) | PTPN1CSKKMT2A | |
| SCHEMBL23332014 | 0.77 | CTSC (0.35) | PTPN1CSKKMT2A | |
| SCHEMBL19884496 | 0.74 | LDHA (0.44) | ACACBCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL24942189 | 0.74 | ACACB (0.48) | POLBACACBPTPN1CSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087083-A1 | USE OF ITACONATE AND ITS DERIVATIVES/ANALOGUES TO INDUCE HAIR GROWTH | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-05-06 | — | — | WO | disclosed |