Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.33 |
| ▸ | CSK | P41240 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.33 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23332014 | 0.91 | CTSC (0.35) | PTPN1SLC7A5CSKHDAC8ALDH1A1 | |
| SCHEMBL24925613 | 0.91 | PTPN1 (0.35) | PTPN1SLC7A5CSKHDAC8ALDH1A1 | |
| SCHEMBL24942214 | 0.87 | PTPN1 (0.33) | PTPN1SLC7A5CSKHDAC8ALDH1A1 | |
| SCHEMBL24942238 | 0.86 | MMP1 (0.36) | PTPN1SLC7A5CSKHDAC8 | |
| SCHEMBL23339153 | 0.83 | ALDH1A1 (0.37) | SLC7A5CSKHDAC8ALDH1A1LMNA | |
| SCHEMBL23332002 | 0.82 | CTSS (0.45) | HDAC8 | |
| SCHEMBL24942202 | 0.79 | CTSC (0.34) | PTPN1SLC7A5CSKHDAC8ALDH1A1 | |
| SCHEMBL23332129 | 0.78 | MGLL (0.42) | HSD17B10DPP7 | |
| SCHEMBL23306559 | 0.78 | MGLL (0.42) | HSD17B10DPP7 | |
| SCHEMBL23338258 | 0.77 | POLB (0.49) | PTPN1CSKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087083-A1 | USE OF ITACONATE AND ITS DERIVATIVES/ANALOGUES TO INDUCE HAIR GROWTH | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-05-06 | — | — | WO | disclosed |
| WO-2021087082-A1 | PRODRUGS OF ITACONATE AND METHYL ITACONATE | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-05-06 | — | — | WO | disclosed |