Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
| ▸ | CA5A | P35218 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | CA3 | P07451 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA6 | P23280 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395454 | 0.82 | CYP19A1 (0.77) | CYP19A1HTTKMT2AGAATSHR | |
| SCHEMBL1171984 | 0.79 | CYP19A1 (0.52) | CYP19A1HTTKMT2AGAACA2 | |
| SCHEMBL1172200 | 0.79 | CA2 (0.66) | CYP19A1HTTKMT2AGAACA2 | |
| SCHEMBL668513 | 0.79 | CYP19A1 (0.52) | CYP19A1HTTKMT2AGAACA2 | |
| SCHEMBL2214769 | 0.79 | CYP19A1 (0.52) | CYP19A1HTTKMT2AGAACA2 | |
| Lithium Ion SCHEMBL28617436 | 0.79 | CYP19A1 (0.52) | CYP19A1HTTKMT2AGAACA2 | |
| SCHEMBL28540842 | 0.79 | CYP19A1 (0.52) | CYP19A1HTTKMT2AGAACA2 | |
| SCHEMBL212845 | 0.79 | CYP19A1 (0.81) | CYP19A1HTTKMT2ATSHRLMNA | |
| SCHEMBL205255 | 0.79 | KMT2A (0.75) | CYP19A1HTTKMT2AGAACA2 | |
| SCHEMBL9577 | 0.78 | CA2 (0.64) | CA2CA5ALMNACA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1211254-B1 | Process for the preparation of benzoxazine derivatives and intermediates therefor | DAIICHI SANKYO CO LTD (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-2284174-B1 | Intermediates for the preparation of benzoxazine derivatives and process for their preparation | DAIICHI SANKYO CO LTD (JP) | 2014-03-05 | — | — | EP | disclosed |
| EP-2218722-B9 | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI SANKYO CO LTD (JP) | 2013-06-19 | — | — | EP | disclosed |
| EP-2218722-B1 | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI SANKYO CO LTD (JP) | 2013-03-13 | — | — | EP | disclosed |
| EP-2360160-A1 | Intermediates and their use for producing benzoxazine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-08-24 | — | — | EP | disclosed |
| CN-101157619-B | Process for producing intermediate for benzoxazine derivative | DAIICHI SEIYAKU CO | 2011-05-04 | — | — | CN | disclosed |
| EP-2284174-A1 | INTERMEDIATES FOR THE PREPARATION OF BENZOXAZINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | Daiichi Sankyo Company, Limited (JP) | 2011-02-16 | — | — | EP | disclosed |
| EP-2218722-A2 | Process for producing benzoxazine derivative and production intermediate thereof | Daiichi Sankyo Company, Limited (JP) | 2010-08-18 | — | — | EP | disclosed |
| CN-100537519-C | Intermediate for preparing benzoxazine derivative and its preparing method | DAIICHI SEIYAKU CO (JP) | 2009-09-09 | — | — | CN | disclosed |
| CN-100432060-C | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI SEIYAKU CO (JP) | 2008-11-12 | — | — | CN | disclosed |
| US-7189847-B2 | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-13 | — | — | US | disclosed |
| US-7087778-B2 | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-08-08 | — | — | US | disclosed |
| CN-1733744-A | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI SEIYAKU CO (JP) | 2006-02-15 | — | — | CN | disclosed |
| US-20060014947-A1 | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI PHARMACEUTICAL CO., LTD. | 2006-01-19 | — | — | US | disclosed |
| CN-1195759-C | Process for preparing benzoxazine derivatives and intermediates thereof | DAIICHI SEIYAKU CO (JP) | 2005-04-06 | — | — | CN | disclosed |
| US-6872823-B1 | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-03-29 | — | — | US | disclosed |
| US-20050027119-A1 | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI PHARMACEUTICAL CO., LTD. | 2005-02-03 | — | — | US | disclosed |
| CN-1532181-A | Intermediate for preparing benzoxazine derivative and preparation method thereof | 第一制药株式会社 | 2004-09-29 | — | — | CN | disclosed |
| CN-1379779-A | Process for preparing benzoxazine derivatives and intermediates thereof | DAIICHI SEIYAKU CO (JP) | 2002-11-13 | — | — | CN | disclosed |
| EP-1211254-A1 | PROCESS FOR THE PREPARATION OF BENZOXAZINE DERIVATIVES AND INTERMEDIATES THEREFOR | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014947-A1 | Process for producing benzoxazine derivative and production intermediate thereof | CYP4Z1, COASY, VAT1 | CYP19A1 210/4885HTT 4170/4885KMT2A 2762/4885 |
| US-20050027119-A1 | Process for producing benzoxazine derivative and production intermediate thereof | CYP4Z1, COASY, VAT1 | CYP19A1 123/4885HTT 4229/4885KMT2A 2115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.