Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.39 |
| ▸ | CASP1 | P29466 | 7/20 | 0.39 |
| ▸ | CASP7 | P55210 | 7/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23340326 | 0.85 | F10 (0.41) | USP2ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23297615 | 0.78 | DPP4 (0.64) | USP2ALDH1A1CYP3A4CYP2C9LMNA | |
| SCHEMBL23340469 | 0.74 | NUDT5 (0.46) | HTR2CNUDT5MAPT | |
| SCHEMBL23340478 | 0.74 | NUDT5 (0.46) | HTR2CLMNASOS1DPP4NUDT5 | |
| SCHEMBL23340460 | 0.74 | POLB (0.39) | HTR2CALDH1A1TP53SOS1DPP4 | |
| SCHEMBL23340704 | 0.73 | NUDT5 (0.56) | HTR2CSOS1DPP4NUDT5L3MBTL1 | |
| SCHEMBL23340639 | 0.73 | NUDT5 (0.47) | HTR2CUSP2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL23340553 | 0.72 | NUDT5 (0.47) | HTR2CALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL23340497 | 0.72 | NUDT5 (0.47) | HTR2CLMNAKMT2ADPP4NUDT5 | |
| SCHEMBL23340461 | 0.72 | NUDT5 (0.46) | HTR2CUSP2ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128566-A1 | NOVEL FUNCTIONALIZED PURINE-2,6-DIONES AND THEIR USE IN MEDICINE | THOMAS HELLEDAYS STIFTELSE FÖR MEDICINSK FORSKNING (SE) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128566-A1 | NOVEL FUNCTIONALIZED PURINE-2,6-DIONES AND THEIR USE IN MEDICINE | ADORA2A, HPRT1, PNP | HTR2C 1202/4885USP2 4150/4885ALDH1A1 333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.