Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | HSD17B13 | Q7Z5P4 | 4/20 | 0.38 |
| ▸ | IDH1 | O75874 | 9/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 3/20 | 0.35 |
| ▸ | CASP7 | P55210 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23340491 | 0.85 | HTR2C (0.43) | F10CYP1A2CASP1CASP7HIF1A | |
| SCHEMBL23340547 | 0.78 | RAB9A (0.50) | USP2TSHRALDH1A1MEN1LMNA | |
| SCHEMBL23340549 | 0.73 | RAB9A (0.38) | TSHRALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL23297752 | 0.72 | HTT (0.58) | CYP1A2CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL23340697 | 0.72 | MEN1 (0.40) | F10HSD17B13TSHRALDH1A1MEN1 | |
| SCHEMBL23340490 | 0.71 | TSHR (0.43) | USP2TSHRALDH1A1MEN1LMNA | |
| SCHEMBL23340327 | 0.71 | CA12 (0.45) | CYP1A2CYP3A4ALDH1A1LMNAKMT2A | |
| SCHEMBL23340492 | 0.70 | ALDH1A1 (0.43) | TSHRALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL23340495 | 0.70 | DRD2 (0.32) | CYP1A2CYP3A4LMNACYP2C9SMN1; SMN2 | |
| SCHEMBL23340548 | 0.69 | RAB9A (0.40) | TSHRALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128566-A1 | NOVEL FUNCTIONALIZED PURINE-2,6-DIONES AND THEIR USE IN MEDICINE | THOMAS HELLEDAYS STIFTELSE FÖR MEDICINSK FORSKNING (SE) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128566-A1 | NOVEL FUNCTIONALIZED PURINE-2,6-DIONES AND THEIR USE IN MEDICINE | ADORA2A, HPRT1, PNP | F10 2542/4885HSD17B13 3999/4885IDH1 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.