Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.30 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23340478 | 0.85 | NUDT5 (0.46) | NUDT5SMN1; SMN2LMNASTAT6 | |
| SCHEMBL23340697 | 0.76 | MEN1 (0.40) | SMN1; SMN2NOTUM | |
| SCHEMBL23340500 | 0.74 | NUDT5 (0.46) | NUDT5SMN1; SMN2CYP1A2CYP2C19LMNA | |
| SCHEMBL23340554 | 0.74 | NUDT5 (0.39) | NUDT5SMN1; SMN2LMNANOTUM | |
| SCHEMBL23340547 | 0.72 | RAB9A (0.50) | NUDT5SMN1; SMN2LMNA | |
| SCHEMBL23297543 | 0.72 | SMN1; SMN2 (0.64) | NUDT5SMN1; SMN2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23340633 | 0.71 | MAPK1 (0.44) | SMN1; SMN2LMNA | |
| SCHEMBL23340490 | 0.70 | TSHR (0.43) | NUDT5SMN1; SMN2LMNA | |
| SCHEMBL23340326 | 0.70 | F10 (0.41) | SMN1; SMN2CYP1A2CYP3A4CYP2C9LMNA | |
| SCHEMBL23340492 | 0.70 | ALDH1A1 (0.43) | SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128566-A1 | NOVEL FUNCTIONALIZED PURINE-2,6-DIONES AND THEIR USE IN MEDICINE | THOMAS HELLEDAYS STIFTELSE FÖR MEDICINSK FORSKNING (SE) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128566-A1 | NOVEL FUNCTIONALIZED PURINE-2,6-DIONES AND THEIR USE IN MEDICINE | ADORA2A, HPRT1, PNP | DRD2 888/4885DRD4 849/4885DRD3 1634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.