Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335120 | 0.86 | FNTA (0.44) | MAPTKMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2337545 | 0.84 | MAPT (0.54) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2336817 | 0.82 | MEN1 (0.52) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL826296 | 0.81 | BRAF (0.60) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL3638532 | 0.79 | FFAR1 (0.47) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL826565 | 0.77 | PTGS1 (0.57) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL3636294 | 0.77 | CDK8 (0.53) | — | |
| SCHEMBL2334105 | 0.74 | KDR (0.55) | MAPTKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2336732 | 0.74 | KDR (0.61) | KMT2ABRAFKDR | |
| SCHEMBL3639218 | 0.74 | KDR (0.41) | POLBMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358689-A1 | Benzothiazole derivatives as anticancer agents | Takeda Pharmaceutical Company Limited (JP) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010064722-A1 | BENZOTHIAZOLE DERIVATIVES AS ANTICANCER AGENTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-10 | — | — | WO | disclosed |