Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.44 |
| ▸ | FNTB | P49356 | 2/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2337545 | 0.86 | MAPT (0.54) | KMT2ASMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL2334149 | 0.86 | POLB (0.47) | KMT2ASMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL3636294 | 0.80 | CDK8 (0.53) | NR1H4THRB | |
| SCHEMBL826173 | 0.79 | BRAF (0.56) | — | |
| SCHEMBL2334105 | 0.77 | KDR (0.55) | NR1H4KMT2ASMN1; SMN2PLAUALDH1A1 | |
| SCHEMBL2336817 | 0.77 | MEN1 (0.52) | KMT2ASMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL2338143 | 0.76 | KMT2A (0.58) | NR1H4KMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL2336732 | 0.76 | KDR (0.61) | KMT2A | |
| SCHEMBL2334508 | 0.74 | KDR (0.72) | KMT2A | |
| SCHEMBL3638532 | 0.73 | FFAR1 (0.47) | NR1H4KMT2ASMN1; SMN2THRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358689-A1 | Benzothiazole derivatives as anticancer agents | Takeda Pharmaceutical Company Limited (JP) | 2011-08-24 | — | — | EP | disclosed |
| WO-2010064722-A1 | BENZOTHIAZOLE DERIVATIVES AS ANTICANCER AGENTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-10 | — | — | WO | disclosed |