SCHEMBL233416

SCHEMBL233416

O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@]2(O)F)c(=O)[nH]1

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 2/20 0.57
SLC28A1 O00337 1/20 0.57
SLC28A2 O43868 1/20 0.57
SLC28A3 Q9HAS3 1/20 0.57
POLA1 P09884 1/20 0.48
P2RY2 P41231 3/20 0.47
P2RY4 P51582 1/20 0.47
PDE4D Q08499 1/20 0.46
PDE3A Q14432 1/20 0.46
P2RY14 Q15391 4/20 0.44
P2RY6 Q15077 2/20 0.41
CDA P32320 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8749574 1.00 SLC29A1 (0.57) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
SCHEMBL1763360 1.00 SLC29A1 (0.57) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
SCHEMBL7876363 1.00 SLC29A1 (0.57) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
Hydrochloric Acid SCHEMBL29938288 0.99 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
Phosphoric Acid SCHEMBL20769291 0.95 SLC28A1 (0.53) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
Phosphoric Acid SCHEMBL4575893 0.95 SLC28A1 (0.53) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
Phosphoramidic Acid SCHEMBL17439381 0.93 SLC29A1 (0.51) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
SCHEMBL12170413 0.88 SLC29A1 (0.59) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
SCHEMBL6758716 0.88 SLC29A1 (0.59) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
SCHEMBL94634 0.88 SLC29A1 (0.59) SLC29A1SLC28A1SLC28A2SLC28A3POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3753 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122095093-A RNAi agents for inhibiting expression of inhibin subunit beta E (INHBE), pharmaceutical compositions and methods of use 2026-05-26 CN claimed
US-20260139251-A1 RNAi Agents for Inhibiting Expression of Mucin 5AC (MUC5AC), Compositions Thereof, and Methods of Use ARROWHEAD PHARMACEUTICALS INC (US) 2026-05-21 US claimed
US-20260132406-A1 RNAi Agents for Inhibiting Expression of Activin Receptor-Like Kinase 7 (ALK7), Compositions Thereof, and Methods of Use ARROWHEAD PHARMACEUTICALS INC (US) 2026-05-14 US claimed
EP-4739343-A2 CIRCULAR RNA VACCINES FOR SEASONAL FLU AND METHODS OF USES Shanghai Circode Biomed Co., Ltd (CN) 2026-05-13 EP claimed
US-20260092276-A1 Carbohydrate-oligonucleotide conjugates, pharmaceutical compositions, and therapeutic applications KYLONOVA XIAMEN BIOPHARMA CO LTD (CN) 2026-04-02 US claimed
US-12582668-B2 Methods for the treatment of alpha-1 antitrypsin deficiency (AATD) Arrowhead Pharmaceuticals, Inc. (US) 2026-03-24 US claimed
US-20260078375-A1 RNAi Agents for Inhibiting Influenza A Viral Gene Expression, Compositions Thereof, and Methods of Use ARROWHEAD PHARMACEUTICALS INC (US) 2026-03-19 US claimed
EP-3573623-B1 COMPOSITIONS AND METHODS FOR INHIBITION OF FACTOR XII GENE EXPRESSION ARROWHEAD PHARMACEUTICALS INC (US) 2026-03-04 EP claimed
US-20260053941-A1 MUSCLE TARGETING COMPLEXES AND FORMULATIONS FOR TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY DYNE THERAPEUTICS, INC. (US) 2026-02-26 US claimed
US-12551569-B2 RNAi agents for inhibiting expression of microtubule associated protein tau (MAPT), compositions thereof, and methods of use Arrowhead Pharmaceuticals, Inc. (US) 2026-02-17 US claimed
US-20020151072-A1 Chimeric mutational vectors VALIGEN (U.S), INC. 2002-10-17 US claimed
EP-1078097-A4 CELL-FREE CHIMERAPLASTY AND EUKARYOTIC USE OF HETERODUPLEX MUTATIONAL VECTORS KIMERAGEN INC (US) 2002-06-05 EP claimed
EP-1084272-A4 HETERODUPLEX MUTATIONAL VECTORS AND USE THEREOF IN BACTERIA KIMERAGEN INC (US) 2002-03-13 EP claimed
US-6211351-B1 FOR INTRODUCTION OF GENETIC CHANGES IN EUKARYOTIC CELLS VALIGEN (US), INC. 2001-04-03 US claimed
EP-1084272-A1 HETERODUPLEX MUTATIONAL VECTORS AND USE THEREOF IN BACTERIA Kimeragen Inc. (US) 2001-03-21 EP claimed
EP-1078097-A1 CELL-FREE CHIMERAPLASTY AND EUKARYOTIC USE OF HETERODUPLEX MUTATIONAL VECTORS Kimeragen Inc. (US) 2001-02-28 EP claimed
US-6010907-A TRANSFORMING TARGET DNA SEQUENCES KIMERAGEN, INC. (US) 2000-01-04 US claimed
US-6004804-A 3'-EXONUCLEASE PROTECTED DUPLEX MUTATIONAL VECTORS; USED TO MAKE SPECIFIC GENETIC ALTERATIONS IN THE GENOME AND IN PLASMIDS OF TARGET PROKARYOTIC CELLS KIMERAGEN, INC. (US) 1999-12-21 US claimed
WO-1999058723-A1 HETERODUPLEX MUTATIONAL VECTORS AND USE THEREOF IN BACTERIA KIMERAGEN, INC. (US) 1999-11-18 WO claimed
WO-1999058702-A1 CELL-FREE CHIMERAPLASTY AND EUKARYOTIC USE OF HETERODUPLEX MUTATIONAL VECTORS KIMERAGEN, INC. (US) 1999-11-18 WO claimed