SCHEMBL8749574

SCHEMBL8749574

O=c1ccn(C2O[C@H](CO)[C@@H](O)[C@@]2(O)F)c(=O)[nH]1

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 2/20 0.57
SLC28A1 O00337 1/20 0.57
SLC28A2 O43868 1/20 0.57
SLC28A3 Q9HAS3 1/20 0.57
POLA1 P09884 1/20 0.48
P2RY2 P41231 3/20 0.47
P2RY4 P51582 1/20 0.47
PDE4D Q08499 1/20 0.46
PDE3A Q14432 1/20 0.46
P2RY14 Q15391 4/20 0.44
P2RY6 Q15077 2/20 0.41
CDA P32320 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL233416 1.00 SLC29A1 (0.57) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
SCHEMBL1763360 1.00 SLC29A1 (0.57) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
SCHEMBL7876363 1.00 SLC29A1 (0.57) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
Hydrochloric Acid SCHEMBL29938288 0.99 SLC29A1 (0.56) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
Phosphoric Acid SCHEMBL20769291 0.95 SLC28A1 (0.53) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
Phosphoric Acid SCHEMBL4575893 0.95 SLC28A1 (0.53) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
Phosphoramidic Acid SCHEMBL17439381 0.93 SLC29A1 (0.51) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
SCHEMBL12170413 0.88 SLC29A1 (0.59) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
SCHEMBL6758716 0.88 SLC29A1 (0.59) SLC29A1SLC28A1SLC28A2SLC28A3POLA1
SCHEMBL94634 0.88 SLC29A1 (0.59) SLC29A1SLC28A1SLC28A2SLC28A3POLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013048952-A1 METHODS AND COMPOSITIONS FOR DETECTING INFECTIONS BIOMED VALLEY DISCOVERIES, INC. (US) 2013-04-04 WO claimed
WO-2013048952-A1 METHODS AND COMPOSITIONS FOR DETECTING INFECTIONS BIOMED VALLEY DISCOVERIES, INC. (US) 2013-04-04 WO disclosed
US-5618803-A TO BRAIN UNIVERSITY OF FLORIDA (US) 1997-04-08 US disclosed
EP-0539493-B1 TARGETED DRUG DELIVERY VIA PHOSPHONATE DERIVATIVES BODOR NICHOLAS S (US) 1997-03-26 EP disclosed
EP-0577725-A4 TARGETED DRUG DELIVERY VIA MIXED PHOSPHATE DERIVATIVES UNIV FLORIDA (US) 1996-04-17 EP disclosed
US-5413996-A Delivery of steroid sex hormone or antiinflammatory steroid to the brain UNIVERSITY OF FLORIDA (US) 1995-05-09 US disclosed
EP-0577725-A1 TARGETED DRUG DELIVERY VIA MIXED PHOSPHATE DERIVATIVES UNIVERSITY OF FLORIDA (US) 1994-01-12 EP disclosed
EP-0539493-A4 TARGETED DRUG DELIVERY VIA PHOSPHONATE DERIVATIVES 1993-06-02 EP disclosed
EP-0539493-A1 TARGETED DRUG DELIVERY VIA PHOSPHONATE DERIVATIVES. BODOR NICHOLAS S (US) 1993-05-05 EP disclosed
US-5177064-A TARGETED DRUG DELIVERY VIA PHOSPHONATE DERIVATIVES UNIVERSITY OF FLORIDA (US) 1993-01-05 US disclosed
WO-1992017185-A1 TARGETED DRUG DELIVERY VIA MIXED PHOSPHATE DERIVATIVES UNIVERSITY OF FLORIDA (US) 1992-10-15 WO disclosed
WO-1992000988-A1 TARGETED DRUG DELIVERY VIA PHOSPHONATE DERIVATIVES BODOR NICHOLAS S (US) 1992-01-23 WO disclosed