Sugi Predict

Sugi Predict / Compounds / SCHEMBL2334255

SCHEMBL2334255

SCHEMBL2334255

NCc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FTO Q9C0B1 10/20 0.70
▸ MAPT P10636 3/20 0.67
▸ HPGD P15428 2/20 0.67
▸ MEN1 O00255 2/20 0.67
▸ HTT P42858 2/20 0.67
▸ KMT2A Q03164 2/20 0.67
▸ CYP2C19 P33261 1/20 0.67
▸ RECQL P46063 1/20 0.67
▸ BLM P54132 1/20 0.67
▸ SMAD3 P84022 1/20 0.67
▸ PRMT1 Q99873 1/20 0.67
▸ ACE2 Q9BYF1 1/20 0.67
▸ TDP1 Q9NUW8 1/20 0.67
▸ GSTP1 P09211 1/20 0.52
▸ ALOX12 P18054 2/20 0.48
▸ ALDH1A1 P00352 2/20 0.48
▸ CYP2C9 P11712 1/20 0.48
▸ ALOX15 P16050 1/20 0.48
▸ BRCA1 P38398 1/20 0.48
▸ HSD17B10 Q99714 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30249984 1.00 FTO (0.70) FTOMAPTHPGDMEN1HTT
Bromide SCHEMBL6999393 0.99 FTO (0.69) FTOMAPTHPGDMEN1HTT
Hydrochloric Acid SCHEMBL1904089 0.99 FTO (0.69) FTOMAPTHPGDMEN1HTT
SCHEMBL1949992 0.91 FTO (0.66) FTOMAPTHPGDMEN1HTT
SCHEMBL29496646 0.91 FTO (0.66) FTOMAPTHPGDMEN1HTT
Bromide SCHEMBL7792912 0.90 FTO (0.64) FTOMAPTHPGDMEN1HTT
Hydrochloric Acid SCHEMBL8542650 0.90 FTO (0.64) FTOMAPTHPGDMEN1HTT
SCHEMBL22772907 0.88 FTO (0.69) FTOMAPTHPGDMEN1HTT
SCHEMBL337558 0.87 FTO (0.67) FTOMAPTHPGDMEN1HTT
SCHEMBL329252 0.87 FTO (0.67) FTOMAPTHPGDMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106967213-A Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2017-07-21 — — CN claimed
US-20070254276-A1 Method and system for measuring membrane potential based on fluorescence polarization SENG ENTERPRISES LTD. (CY) 2007-11-01 — — US claimed
US-6794158-B2 FLUORESCENT PROBE FOR USE AS DIAGNOSTIC TOOL IN MONITORING PREFERENTIAL ENZYME ACTIVITY BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 2004-09-21 — — US claimed
EP-0853680-B1 METHOD FOR PRECIPITATING NUCLEIC ACID WITH VISIBLE CARRIER EMD BIOSCIENCES INC (US) 2004-03-31 — — EP claimed
US-20030082665-A1 Fluorescence polarization assay BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 2003-05-01 — — US claimed
WO-2002082082-A2 FLUORESCENCE POLARIZATION ASSAY BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2002-10-17 — — WO claimed
US-20010010920-A1 Monoclonal antibodies obtained using rapamycin position 27 conjugates as an immunogen WYETH 2001-08-02 — — US claimed
EP-0702689-A4 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS ABBOTT LAB (US) 1997-10-22 — — EP claimed
US-5648272-A Reagents and methods for the detection and quantification of thyroxine in fluid samples ABBOTT LABORATORIES (US) 1997-07-15 — — US claimed
EP-0710110-A4 RAPAMYCIN CONJUGATES AND ANTIBODIES ABBOTT LAB (US) 1997-06-18 — — EP claimed
US-5424414-A Haptens, tracers, immunogens and antibodies for 3-phenyl-1-adamantaneacetic acids ABBOTT LABORATORIES (US) 1995-06-13 — — US claimed
EP-0649533-A1 REAGENTS AND METHODS FOR THE DETECTION AND QUANTIFICATION OF THYROXINE IN FLUID SAMPLES ABBOTT LABORATORIES (US) 1995-04-26 — — EP claimed
WO-1995003296-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR CARBAZOLE AND DIBENZOFURAN DERIVATIVES ABBOTT LABORATORIES (US) 1995-02-02 — — WO claimed
WO-1994029329-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS ABBOTT LABORATORIES (US) 1994-12-22 — — WO claimed
WO-1994025022-A1 RAPAMYCIN CONJUGATES AND ANTIBODIES ABBOTT LABORATORIES (US) 1994-11-10 — — WO claimed
WO-1993020074-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR ACRIDINE-9-CARBOXYLIC ACIDS ABBOTT LABORATORIES (US) 1993-10-14 — — WO claimed
WO-1993020094-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR QUINOLINE ABBOTT LABORATORIES (US) 1993-10-14 — — WO claimed
WO-1993020442-A1 REAGENTS AND METHODS FOR THE DETECTION AND QUANTIFICATION OF THYROXINE IN FLUID SAMPLES ABBOTT LABORATORIES (US) 1993-10-14 — — WO claimed
US-5145790-A Immunoassay, fluorescein derivative ABBOTT LABORATORIES (US) 1992-09-08 — — US claimed
EP-0455058-A2 Reagents and method for detecting polychlorinated biphenyls ABBOTT LABORATORIES (US) 1991-11-06 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010010920-A1 Monoclonal antibodies obtained using rapamycin position 27 conjugates as an immunogen RICTOR, MLST8, MAPKAP1 FTO 3602/4885MAPT 2299/4885HPGD 2995/4885
US-20030082665-A1 Fluorescence polarization assay EPHX1, EPHX2, LTA4H FTO 539/4885MAPT 4854/4885HPGD 127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.