Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 2/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23343010 | 0.79 | USP30 (0.48) | L3MBTL1CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL23342998 | 0.79 | USP30 (0.48) | L3MBTL1CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL28838656 | 0.79 | USP30 (0.48) | L3MBTL1CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL23342997 | 0.79 | USP30 (0.48) | L3MBTL1CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL28838706 | 0.79 | USP30 (0.48) | L3MBTL1CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL7657426 | 0.79 | L3MBTL1 (0.42) | L3MBTL1GPR119MAPTMAPK1NPSR1 | |
| SCHEMBL16847349 | 0.76 | MEN1 (0.57) | CYP2C19GPR119MAPTNPSR1MEN1 | |
| SCHEMBL32677602 | 0.76 | JAK2 (0.51) | L3MBTL1GPR119MAPTMAPK1NPSR1 | |
| SCHEMBL30922790 | 0.75 | USP30 (0.51) | L3MBTL1CYP3A4CYP2C9CYP2C19GPR119 | |
| SCHEMBL24708468 | 0.75 | MAPT (0.46) | L3MBTL1CYP3A4CYP2C9CYP2C19GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210130326-A1 | RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130326-A1 | RAS INHIBITORS | KRAS, NRAS, HRAS | L3MBTL1 3097/4885CYP3A4 3780/4885CYP2C9 3961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.