Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 3/20 | 0.41 |
| ▸ | KRAS | P01116 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28798525 | 0.87 | SOS1 (0.39) | SOS1KRASLMNACYP1A2CYP3A4 | |
| SCHEMBL21132431 | 0.87 | SOS1 (0.39) | SOS1KRASLMNACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL25364056 | 0.85 | SOS1 (0.39) | SOS1KRASLMNACYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL25248688 | 0.85 | SOS1 (0.39) | SOS1KRASLMNACYP1A2CYP3A4 | |
| SCHEMBL21936938 | 0.83 | KRAS (0.33) | SOS1KRASGABRA1GABRG2GABRB3 | |
| SCHEMBL24802168 | 0.83 | SOS1 (0.36) | SOS1KRAS | |
| SCHEMBL8121999 | 0.81 | PTGS1 (0.36) | SOS1KRASGABRA1GABRG2GABRB3 | |
| SCHEMBL21911577 | 0.79 | GABRA1 (0.35) | SOS1KRASGABRA1GABRG2GABRB3 | |
| SCHEMBL29473829 | 0.78 | GABRA1 (0.38) | SOS1KRASGABRA1GABRG2GABRB3 | |
| SCHEMBL26017558 | 0.77 | SOS1 (0.41) | SOS1KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011540-A1 | FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | 苏州信诺维医药科技股份有限公司 | 2023-02-09 | — | — | WO | disclosed |
| US-20210139517-A1 | BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF | Revolution Medicines, Inc. | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139517-A1 | BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF | SOST, SOS1, SOS2 | SOS1 2/4885KRAS 14/4885GABRA1 962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.