Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21132431 | 0.87 | SOS1 (0.39) | SOS1KRAS | |
| SCHEMBL28798525 | 0.87 | SOS1 (0.39) | SOS1KRAS | |
| Hydrochloric Acid SCHEMBL25248688 | 0.85 | SOS1 (0.39) | SOS1KRAS | |
| Hydrochloric Acid SCHEMBL25364056 | 0.85 | SOS1 (0.39) | SOS1KRAS | |
| SCHEMBL23344916 | 0.83 | SOS1 (0.41) | SOS1KRAS | |
| SCHEMBL21132537 | 0.73 | KRAS (0.34) | SOS1KRAS | |
| SCHEMBL24343563 | 0.73 | — | — | |
| SCHEMBL24801882 | 0.72 | PNMT (0.33) | — | |
| Hydrochloric Acid SCHEMBL28668494 | 0.70 | ALDH1A1 (0.36) | SOS1KRAS | |
| SCHEMBL22234725 | 0.70 | PARP1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271679-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |