Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23995728 | 0.84 | — | — | |
| SCHEMBL23344924 | 0.80 | CA2 (0.38) | CA2GABRA1GABRB2 | |
| SCHEMBL23344919 | 0.80 | CA2 (0.38) | CA2GABRA1GABRB2 | |
| SCHEMBL29861343 | 0.75 | CYP1A2 (0.37) | GABRA1 | |
| SCHEMBL23326480 | 0.75 | CYP1A2 (0.37) | GABRA1 | |
| SCHEMBL23326479 | 0.75 | CYP1A2 (0.37) | GABRA1 | |
| SCHEMBL23326470 | 0.75 | CSNK2A1 (0.30) | — | |
| SCHEMBL31454573 | 0.75 | KDM4E (0.30) | — | |
| SCHEMBL29861359 | 0.75 | CSNK2A1 (0.30) | — | |
| SCHEMBL23326329 | 0.72 | KMT2A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139517-A1 | BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF | Revolution Medicines, Inc. | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139517-A1 | BICYCLIC HETEROARYL COMPOUNDS AND USES THEREOF | SOST, SOS1, SOS2 | CA2 3381/4885GABRA1 962/4885GABRB2 1186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.