SCHEMBL31454573

SCHEMBL31454573

N#CCc1c(I)cccc1C(F)F

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23326470 0.79 CSNK2A1 (0.30) KDM4ETDP1
SCHEMBL29861359 0.79 CSNK2A1 (0.30) KDM4ETDP1
SCHEMBL29861343 0.76 CYP1A2 (0.37)
SCHEMBL23326479 0.76 CYP1A2 (0.37)
SCHEMBL23326480 0.76 CYP1A2 (0.37)
SCHEMBL24597276 0.76 GABRA1 (0.32)
SCHEMBL31454642 0.76 MEN1 (0.34) KDM4ETDP1
SCHEMBL23344918 0.75 CA2 (0.33)
SCHEMBL23326329 0.72 KMT2A (0.37) KDM4E
SCHEMBL29861743 0.72 KMT2A (0.37) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119977947-A PRMT5 inhibitor, pharmaceutical composition thereof and application of PRMT5 inhibitor in medicines 广东东阳光药业股份有限公司 2025-05-13 CN disclosed