Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335553 | 1.00 | POLB (0.44) | POLBEPHX2NPC1ELANETSHR | |
| SCHEMBL2331257 | 1.00 | POLB (0.44) | POLBEPHX2NPC1ELANETSHR | |
| SCHEMBL2339438 | 0.86 | POLB (0.49) | POLBEPHX2NPC1TSHRALDH1A1 | |
| SCHEMBL2334831 | 0.86 | POLB (0.49) | POLBEPHX2NPC1TSHRALDH1A1 | |
| SCHEMBL2337104 | 0.86 | POLB (0.49) | POLBEPHX2NPC1TSHRALDH1A1 | |
| SCHEMBL2331330 | 0.79 | ALDH1A1 (0.46) | POLBEPHX2NPC1ALDH1A1HTT | |
| SCHEMBL2331584 | 0.79 | ALDH1A1 (0.46) | POLBEPHX2NPC1ALDH1A1HTT | |
| SCHEMBL2331329 | 0.79 | ALDH1A1 (0.46) | POLBEPHX2NPC1ALDH1A1HTT | |
| SCHEMBL20804539 | 0.77 | SMN1; SMN2 (0.40) | ELANETSHRTDP1SMN1; SMN2KDM4E | |
| SCHEMBL9376422 | 0.76 | CYP1A2 (0.58) | POLBEPHX2NPC1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2360160-A1 | Intermediates and their use for producing benzoxazine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-08-24 | — | — | EP | disclosed |