Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2339438 | 1.00 | POLB (0.49) | POLBMEN1KMT2ANPC1HTT | |
| SCHEMBL2337104 | 1.00 | POLB (0.49) | POLBMEN1KMT2ANPC1HTT | |
| SCHEMBL2334589 | 0.86 | POLB (0.44) | POLBNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL2335553 | 0.86 | POLB (0.44) | POLBNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL2331257 | 0.86 | POLB (0.44) | POLBNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL2331584 | 0.83 | ALDH1A1 (0.46) | POLBNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL2331330 | 0.83 | ALDH1A1 (0.46) | POLBNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL2331329 | 0.83 | ALDH1A1 (0.46) | POLBNPC1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL2331577 | 0.77 | EPHX2 (0.51) | POLBMEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL16059705 | 0.77 | MEN1 (0.66) | POLBMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2360160-A1 | Intermediates and their use for producing benzoxazine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-08-24 | — | — | EP | disclosed |